Is creatinine 300 high for chronic kidney disease? Creatinine is the product 
from muscle’s metabolism which occurs in human body. 20g muscle can produce 1mg 
creatinine. It is excreted via the glomerular filtration in the kidney. Serum 
creatinine in the normal body represents 44—133μmoI/L.
So once creatinine is high, more than the normal range, it indicates that the 
damage in the kidney takes place, the detailed one of which are as follows:
In the compensation stage, serum creatinine is 133 to 177umol/L. In this 
stage, patients generally have no symptoms, or they can only feel weakness, 
soreness of the waist, and increased urine at night.
In the discompensation stage, serum creatinine is 177 to 442 umol/L. In this 
stage, patients feel poor appetite, slight anemia and slight acidosis.
In the early stage of renal failure, serum creatinine is 442 to 707 umol/L. 
In this stage, the above mentioned symptoms become more obvious.
In the advanced stage of renal failure, serum creatinine is more than 707 
umol/L.
In general, only after kidney function is lost more than half, serum 
creatinine begins to rise. It can also explain why after we donate a kidney, we 
can still live well. Kidney really has a strong compensation ability, which 
means that after some renal glomerulus are damaged, other will do their work 
till they fail. In this case, serum creatinine rises. Serum creatinine can even 
rise as high as more than 2000 umol/L.
Creatinine 300 umol/L means that chronic kidney disease patients are in 
discompensation stage. If not treated well, patients will go to renal failure 
stage. So the treatment in this stage is critical. How to treat it effectively 
so that we can reverse?
The reason why serum creatinine is high is that the renal glomerular 
filtration membrane is damaged. As long as we repair the damaged renal 
glomerular filtration membrane, we can stop the high creatinine. Micro-Chinese 
Medicine Osmotherapy in Shijiazhuang Kidney Disease Hospital can solve the 
problem. It contains active herbs which can extend blood vessels, promote the 
blood circulation, relieve the insufficiency of blood and oxygen in the kidney. 
After that, the nutrition can repair the damaged cells, thus reducing the 300 
high creatinine.