2012年6月17日星期日

Hematuria how the diagnosis of children with IgA nephropathy


Children with IgA nephropathy hematuria do renal biopsy? Often puzzling for parents, let the experts give you more explanation: As can be seen from the clinical records, the performance of isolated hematuria in children with IgA nephropathy male, episodes of gross hematuria more common, with an average age of 10. often serum IgA levels increased, and often respiratory tract infection incentives, IgA nephropathy Lee pathologic grading of three, often kidney adverse pathological findings, early renal biopsy guidance and treatment, to determine and improve the prognosis, but not according to serious hematuria degree of judgment pathological severity, even if only microscopic hematuria should also be early renal biopsy; isolated hematuria children with IgA nephropathy patients need long-term follow-up, monitoring blood pressure, proteinuria and renal function indicators of progress; on children with IgA nephropathy treatment, as some cases of chronic renal failure may occur after several years, the protection of renal function, slow disease progression is the key to treatment.
What isolated hematuria in IgA nephropathy: children with IgA nephropathy isolated hematuria is the urinary red blood cell count more than normal, without high blood pressure and other clinical symptoms without proteinuria and renal function changes in children IgA nephropathy.
IgA nephropathy pathology is characterized by glomerular mesangial diffuse IgA deposition, with varying degrees of Focal Segmental Glomerulosclerosis(FSGS) or diffuse mesangial proliferation, and diverse clinical manifestations, the most common isolated hematuria. Children with IgA nephropathy accounted for 40.6 percent of children with isolated hematuria of children with isolated hematuria the most common reason. Previously considered pathological light of the performance of isolated hematuria in children with IgA nephropathy, the prognosis is good, less renal biopsy, in recent years that some patients need to line the renal biopsy and treatment of the controversy. Most scholars believe that the renal biopsy in children with IgA nephropathy at an early stage to determine the treatment of children with IgA nephropathy isolated hematuria.

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