The death rate of those people who have Chronic Kidney Disease (CKD) and
cardiovascular disease together is 10~30 times higher than that of common
people. An epidemic research demonstrates that 8% of people (esp. senior
citizens) have chronic renal insufficiency. Among them, cardiovascular diseases
are the most common complications, and the heavier the renal insufficiency is,
the higher the morbidity of cardiovascular disease will be.
Traditional influencing factors such as Hypertension, Hyperlipidemia,
Diabetes and smoking still indicate a poor prognosis among sufferers with
Chronic Kidney Disease. Moreover, the influence of high blood pressure on
sufferers with Chronic Kidney Disease may be much higher. They often have an
elevated homocysteine, oxidative stress, disordered lipid metabolism, increased
inflammation markers, and abnormal metabolism of calcium and phosphorus, which
reduce the smoothness of blood vessels so as to promote the formation of
atherosclerosis.
In the development process, diabetes sufferers always have Chronic Kidney
Disease. Clinical cases illustrate that when Diabetic Nephropathy sufferers have
micro-albumin in their urine, they are always accompanied with uncontrolled
glucose, high blood pressure, carotid artery incrassation and other types of
coronary disease. The death rate of those who have micro-albumin urine together
with diabetes is higher than that of those who have no micro-albumin urine. They
are very likely to die from myocardial infarction, apoplexy or other
cardiovascular diseases, because they have more risk factors such as obstructed
function of endothelium, abnormal fibrinolysis coagulation syImmunotherapy and
inflammation. Also, micro-albumin urine may indicate renal insufficiency.
The morbidity of myocardosis among sufferers with Chronic Kidney Disease is
also very high. High blood pressure and atherosclerosis lead to the incrassation
of left ventricular. In addition, Anemia and arteriovenous fistula can cause
excessive volume load. These abnormal changes in heart structure will arouse
obstruction in ventricle, with heart failure and myocardial ischemia as its
clinical manifestations. In particular, those people who are undergoing dialysis
often have Hypertension or Hypotension because of water and sodium retention.
Heart failure is the manifestation of severe cardiovascular disease and is a
risk factor for a poor prognosis.
Cardiovascular Disease is a most common and serious complication of Chronic
Kidney Disease. In order to prevent cardiovascular diseases, Chronic Kidney
Disease should be treated effectively and fundamentally to remit the risk
factors in causing cardiovascular diseases.
