Renal Anemia refers to the Anemia which appears when various kinds of chronic
kidney disease (CKD) develops into renal failure, and among them, the one caused
by chronic renal failure is always the most serious one. Many patients go to
hospital just because the Anemia and then are detected with chronic kidney
disease.
When serum creatinine rises up to 309μmol/L (3.5mg/dL), most of the patients
get Anemia, which aggravates chronic kidney disease further. There are many
cause of the Anemia, including:
1. The amount of EPO, which is secreted by kidney, decreases.
2. There are some substances in blood that can restrict the function of red
blood cells.
3. The lifespan of red blood cells declines.
4. There is lack of ferrum and folacin, and malnutrition also occurs.
5. Blood losing due to bleeding or blood drawing.
6. Hyperparathyroidism.
7. Secondary infection.
8. Aluminium poisoning.
The following presentations are helpful for the diagnosis of renal
Anemia.
◆ Renal dysfunction, and serum creatinine is up to 309μmol/L (3.5mg/dL),
accompanying with electrolyte disturbance and acid base imbalance.
◆ The simple renal Anemia always presents normal cells, but if there is
ferrum and folacin deficiency, hypochromic microcytic Anemia will appear.
◆ In most cases, white blood cells and blood platelet are still normal, but
the quantity of neutrophil drops.
◆ Red blood cell count and megakaryocyte are normal.
◆ The time of ferrum disappearance is normal or longer, the rate of
conversion of ferrum is normal or lower, the use ratio of ferrum drops, the
content of ferrum in serum is normal or higher.
◆ The content of serum folacin is lower, but in the red blood cells
normal.
◆ EPO in serum become less, and general anti-anemia medicine has no
effect.
Chronic kidney disease often leads to Renal Anemia, and renal Anemia
exacerbates chronic kidney disease further at the same time. Many patients in
clinic go to hospital just because of Anemia, and then they are detected with
chronic kidney disease. Renal Anemia aroused by Polycystic kidney disease (PKD)
or Hypertensive Nephropathy is somewhat slighter, but the one aroused by
nephrectomy, and chronic kidney disease accompanied with Nephrotic Syndrome or
serious hyperparathyroidism is usually severer. If you have any related
question, leave a message.
