CKD can be divided into 5 stages. In stage 4, GFR falls to 15~29 ml/min. 
Serum creatinine rises to 451-707umol/L. In this stage, patients can have 
symptoms such as fatigue, poor appetite, slight anemia, high blood pressure, the 
less absorption of calcium, etc. Anemia makes people look pale and the skin also 
looks dark. How to treat it?
Firstly, we should figure out the causes which can help us choose specific 
and scientific therapeutic method.
1. The generation of red blood cells declines. The common factors are the 
decreased generation of EPO, the function of inhibiting factor which inhibit the 
generation of red blood cells, insufficiency of vitamin and trace elements.
2. The lifespan of red blood cells are damaged, the main factors of which are 
such as toxins in the body caused by uremia, endocrine hormone, etc.
3. Increased lost of red blood cells. Most patients who have renal anemia 
have abnormal renal function. Blood urine nitrogen and serum creatinine 
increases, which even rises as high as that in End Stage Renal Disease(ESRD) stage.
From the above, we can know that if we want to treat anemia in stage 4 
chronic kidney disease, we should try to rebuild renal function by repairing 
normal renal function. How to repair the kidney damaged intrinsic cells.
Chinese medicine, especially Micro-Chinese Medicine Osmotherapy can treat 
renal anemia from root for it repair the above mentioned kidney structure. 
Micro-Chinese Medicine is advanced compared with traditional Chinese medicine 
for it is applied through osmosis, which can prevent poor appetite caused by 
long time oral application of Chinese medicine. Secondly, it is abstracted from 
herbs of nature, which contains more than 10 trace elements such as iron, folic 
acid, and so on, which can relieve anemia fundamentally.
In this way, damaged intrinsic cells are damaged, anemia in stage 4 chronic kidney disease can be relieved.
