2015年8月5日星期三

The Influence of Chronic kidney Disease(CKD) on Prognosis of Coronary Artery Disease

In resent years, Chronic Kidney Disease (CKD) patients with coronary heart disease have obviously higher fatality rate, especially the end-stage CKD patients. What is the relationship between Chronic Kidney Disease (CKD) and coronary heart disease? To get the answer, our hospital conducts a research and investigation in detail.Chronic Kidney Disease(CKD) Stage 4 Chronic Kidney Disease(CKD) Stage 3

In order to investigate the influence of chronic kidney disease(CKD),including slight renal damages, on prognosis of coronary artery disease, a methods is adopted here in our hospital,i.e. a retrospective study was performed in 877 patients who visited our hospital in 2006-2010.All patients suspected of coronary artery disease underwent a selective coronary angiography. Five hundred and seventy-nine patients with established diagnosis of coronary artery disease were followed up and their cardiovascular events were recorded.
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According to the degree of renal function damages patients with coronary artery disease were divided into normal, slight, moderate and severe groups. The influences of different degrees of renal damages on the prognosis of coronary artery disease were compared. The research results shows that there were obvious differences in the morbidities of angina pectoris, myocardial infarction, recurrent myocardial infarction, heart failure, stroke, etc. in coronary artery disease patients with different degrees of renal function damages. The worse the renal function, the higher the incidences of angina pectoris, myocardial infarction, recurrent myocardial infarction, heart failure and stroke, etc(P<0.05). The conclusion is reached that the severity of chronic renal insufficiency is positively correlated to the risks of coronary artery disease. The worse the renal function is, the higher the incidence of cardiovascular events and the worse the prognosis.

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