2011年12月21日星期三

kidney disease and diabetes


Diabetes mellitus, often simply referred to as diabetes, is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin that is produced. This high blood sugar produces the classical symptoms of polyuria (frequent urination), polydipsia (increased thirst) and polyphagia (increased hunger).
All forms of diabetes increase the risk of long-term complications. These typically develop after many years (10–20), but may be the first symptom in those who have otherwise not received a diagnosis before that time. The major long-term complications relate to damage to blood vessels.Diabetic retinopathy, which affects blood vessel formation in the retina of the eye, can lead to visual symptoms, reduced vision, and potentially blindness. Diabetic nephropathy, the impact of diabetes on the kidneys, can lead to scarring changes in the kidney tissue, loss of small or progressively larger amounts of protein in the urine, and eventually chronic kidney disease requiring dialysis. Diabetic neuropathy is the impact of diabetes on the nervous system, most commonly causing numbness, tingling and pain in the feet and also increasing the risk of skin damage due to altered sensation. Together with vascular disease in the legs, neuropathy contributes to the risk of diabetes-related foot problems (such as diabetic foot ulcers) that can be difficult to treat and occasionally require amputation.
Diabetic Nephropathy is one of diabetes complication. It due to kidney disease, What are kidney disease.Chronic kidney disease includes conditions that damage your kidneys and decrease their ability to keep you healthy by doing the jobs listed. If kidney disease gets worse, wastes can build to high levels in your blood and make you feel sick. You may develop complications like high blood pressure, anemia (low blood count), weak bones, poor nutritional health and nerve damage. Also, kidney disease increases your risk of having heart and blood vessel disease. These problems may happen slowly over a long period of time. Chronic kidney disease may be caused by diabetes, high blood pressure and other disorders. Early detection and treatment can often keep chronic kidney disease from getting worse. When kidney disease progresses, it may eventually lead to kidney failure, which requires dialysis or a kidney transplant to maintain life.
Now there is a question : Kidney Disease from Longterm Diabetes: Symptoms, Prevention and Treatment. (It is from http://www.diabetes-kidney.org)
What are the common symptoms of Diabetic Nephropathy(Kidney Disease)
1. Proteinuria
Proteinuria, or protein in urine, is a typical symptom of Diabetic nephropathy. Increased protein output in urine indicates damaged glomerular basement membrane caused by high blood sugar. The amount of protein in urine increases with more and more renal intrinsic cells damaged.
While microalbuminuria(30-300mg/24h) appears in preclinical stage of Diabetic Nephropathy, heavy proteinuria(>3.5g/24h) indicates that the disease has entered Clinical Stage and will deteriorate into end-stage rapidly if not treated.
2.Swelling
Prevention and treatment
1. Controlling risk factors
2. Proper diet
3. Combination of traditional Chinese medicine and stem cell transplant.
IF you have kidney disease, You need pay attenton to kidney .

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