During the treatment of lupus nephritis, it is very important to control the 
activity of lupus by using immunosuppressive. However, protection of kidneys 
should not be neglected, otherwise the treatment would fail, only to cause renal 
insufficiency. In fact, if the damage caused by SLE on kidneys is severe, the 
pathological changes would only continue even if the lupus is inactive. 
Eventually, the kidneys would harden, resulting in renal insufficiency. So, 
during the treatment of lupus nephritis, it makes great sense for the patients 
to protect their kidney functions. So, what risk factors would aggravate the 
kidney conditions?
The first is hypertension.
Hypertension is a common complication for patients with lupus nephritis, and 
it is also a major risk factor for kidney deterioration. Thus, patients with 
lupus nephritis should monitor their blood pressure regularly. Rising blood 
pressure should be controlled once spotted.
The second is proteinuria(protein in urine).Proteinuria and Kidney Disease
Proteinuria not only is indicative of glomerular damage, but also can harm 
the interstitium and tubules, which would an independent risk factor for the 
development of kidney disease. Reducing proteinuria can relieve the damage on 
kidneys and protect kidneys. ACEI( such as Lotensin) and ARB(such as 
Diovan)could help reduce protein in urine and lessen kidney hardening, thus 
protecting kidneys.Stem Cell Therapy for Lupus Nephritis Treatment for Lupus Nephritis, Creatinine 5.6 With Joint Pain Symptoms and Treatment for Lupus Nephritis Class 4
The third is nephro-toxic medications.
Some medications are harmful to the kidneys, such as sulfanilamide, 
kanamycin, gentamicin, polymyxin B and some pain-killers. For patients with 
lupus nephritis, they should avoid these medicines in case of further damage to 
kidneys.
The fourth is infection.Hot Compress Therapy for Kidney Disease Acupuncture for Kidney Disease
During the treatment of lupus nephritis, especially in the initial months, 
patients are likely to contract infections. Infection would lead to relapse or 
aggravation, so patients should avoid infection in their daily lives, steer away 
from public places, keep their homes clean. Once infection happens, they should 
go to doctor immediately.Treatment for Stage 4 Lupus Nephritis
The fifth is obesity.
Obesity is public issue worldwide. It is not only a risk factor for 
hypertension, coronary heart disease and hyperlipemia, but also increase 
proteinuria and aggravate kidney functions.
If the patients with lupus nephritis are also obese, they should lose 
weight.
Other conditions like cardiac insufficiency, acidosis, electrolyte disorder 
and hyperlipidemia should also be addressed during the treatment.
