Brief Analysis of polycystic kidney disease (PKD) kidney disease

Polycystic kidney disease (PKD) is a hereditary disease, and its main symptoms of growth and a large number of cysts on the kidneys. The human body has two kidneys, and kidney size of a fist, located in the hips. The main function of the kidneys is to filter blood of metabolic wastes and excess water, and the form of urine excreted. In addition, the kidney is also responsible for regulating the body electrolyte balance and acid base balance. Due to the growth of fluid-filled cyst on the kidney, these cysts will change the normal organizational structure of the kidney resulting in kidney larger size and functional decline until renal failure.
Under normal circumstances, will take years PKD to the development of renal failure, but once they reach the degree of renal failure, it means that patients need dialysis or kidney transplantation. About half of patients with polycystic kidney the development of renal failure, or ESRD.
PKD also lead to liver cyst, and other organ diseases, such as brain vascular or cardiovascular disease. The doctors are often based on the number of cysts and the complications of type to distinguish normal renal cysts and polycystic kidney disease.
The United States there are approximately 600,000 patients with polycystic kidney, and cystic lesions is the fourth largest cause leading to renal failure. There are two main hereditary polycystic kidney disease type:
Autosomal dominant polycystic kidney is the most common form of hereditary polycystic kidney disease kidney disease. Its main incidence of the crowd of about 30-40 young people, but there may be an earlier onset even in patients with childhood onset.Approximately 90% of ADPKD patients fall into this category.
Autosomal recessive polycystic kidney disease, compared with the rare hereditary polycystic kidney disease kidney disease. Incidence of very early onset is usually in the first few months after the birth of the patients, even patients had onset in utero.