What are the causes of elevated creatinine level? Creatinine is a metabolism
product from muscles. The creatinine is dischareged out of the body through
renal glomerular filtration membrane. In the renal glomerular filtration
membrane, there are small pores, through which, creatinine can come out into
urine. Normally, the serum creatinine is 44 to 103umol/L.
Once kidney or renal glomerular filtration membrane is damaged, creatinine
will not discharge out. So serum creatinine becomes high. And creatinine in
urine becomes low. Actually, in normal condition, creatinine level in urine
should be higher than the level of serum creatinine.
And normally, secrum creatinine level will not rise even kidney is damaged,
which is because kidney has a strong ability of compensation. When some
glomeruli are damaged, other healthy glomeruli can replace and do more work,
which leads the serum creatinine to stay in normal condition. So once serum
creatinine rises, it means that the damage is more than 50% in the kidney.
So once we have found out that the serum creatinine is high, even a little
high, we should attach importance on it. Besides this, the following factors can
also lead to the elevated serum creatinine.
1. People who have renal insufficiency can have temporarily elevated serum
creatinine due to infections such as cold, urinary infection, etc.
2. People lost a lot of water due to fever, sweat, less amount of water
intake, etc, which leads to the less blood flow in the kidney, thus causing
temporary elevated serum creatinine.
3. People who have had kidney disease take in medicine which does harm to the
kidney, which will also lead to the elevated serum creatinine. It can be
reversible.
4. The relapse of kidney disease can also lead to the elevated serum
creatinine as well.
5. Due to fatigue, not enough rest, etc, elevated serum creatinine can also
take place.
