GFR, shortened for Glomerular Filtration Rate, refers to a rate at which
kidneys get what the body does not need out. It has normal range which is above
90. The value you get is below 60, which indicates your kidneys are working
abnormally and you may have got kidney disease and if your value is below 15,
your kidney disease is so serious that you’d better to take some actions or you
may be at risk of a series problems.
Why do gfr levels decrease?
GFR is an indicator of the filtration function of kidneys. Kidney filtration
function is mainly worked by millions of glomeruli which have the function of
filtering wastes out of the blood. So,
GFR is actually an indicator of how well the glomeruli are working.
Therefore, to improve GFR is to improve the filtration function of
glomeruli.
Why does the filtration of glomeruli decrease?
The decreased filtration of glomeruli is the result of damaged or injured
glomeruli. Although there are many reasons causing decreased filtration of
glomeruli, the mainly reason is related to abnormal immune syImmunotherapy which
produce immune complex. Accumulation of immune complex will damage kidney
intrinsic cells, including glomeruli, and kidney tissues. To improve GFR is to
repair the damaged kidney cells and tissues, which requires clearing the immune
complex out.
How to clear immune complex?
Firstly, know clearly about the position that immune complex deposits. Only
knowing the exact position the immune complex deposits can we have a goal of
where to be treated.
Secondly, prevent continuing accumulation of immune complex. The abnormal
immune Immunotherapy contributes to producing lots of immune complex. In order
to avoid the further deposition, we should interrupt depositing immune
complex.
Thirdly, clear the immune complex. Unique techniques, including plasma
exchange, Blood Purification and other effective methods are applied to achieve
this goal.
After the gone of immune complex, the damaged kidneys can be repaired, then
the GFR will be improved.