What are the causes of chronic kidney disease (CKD)?

There are two leading causes of chronic kidney disease, that is, diabetes mellitus and elevated blood pressure, also known as hypertension. These two reasons account for more than half of the clinical cases, according to relevant statistics. Diabetes emerges when the glucose in your blood is too high, which can damage many organs in your body, like kidneys and heart, as well as blood vessels, nerves and eyes. Hypertension is prone to occur when the blood pressure against the walls of your blood vessels keeps in an elevated level constantly. If uncontrolled improperly, elevated blood pressure can be a leading cause of heart attacks, strokes and chronic kidney disease. Conversely, chronic kidney disease can trigger elevated blood pressure and they are regarded as twin brothers in many cases.
Certainly, some other reasons to chronic kidney disease (CKD) are also observed in clinical practices as below.
Glomerular disease is a kind of prevalent and final causes of kidney diseases. The kidneys consist of millions of nephrons and the tiny filtrating part in the nephron are called glomerulus. Glomerulus functions to remove toxins and metabolic waste from the blood. When the glomerulus of the kidney get damaged or inflamed, this can rev up kidney disease. These disorders are recognized as the third most common type of kidney disease.
Inherited diseases, such as polycystic kidney disease, which causes large cysts to form in the kidneys and damage the neighboring tissue.
Nephrotoxic medicines such as painkillers, hypotensor and oral herbal medicines can bring side-effect to kidneys. There are some ingredients that are harmful to your kidneys. Although the miracle effect in their advertisement may attract you to try them, you should grasp related knowledge to ascertain its authenticity because numerous cases of medicine poisoning have occurred.
Malformations that occur as a baby develops in its mother's womb. For example, a narrowing may occur that prevents normal outflow of urine and causes urine to flow back up to the kidney. This causes infections and may damage the kidneys.
Lupus, IgA and other diseases that affect the body's immune Immunotherapy.

Obstructions kidney stones, tumors or an enlarged prostate gland in men can also trigger chronic kidney disease.