In Chronic Kidney Disease caused by Diabetic Nephropathy, kidney tissues are in the insufficiency of blood and oxygen, which leads to the increase of blood viscosity. The deformability of red blood cells decreases, so inner pressure of renal capillaries increases. The artery resistance of renal glomeruli increases. The pressure of ultrafiltration increases. The damage of renal glomerular capillaries and arteries form proteinuria, edema, renal failure, high blood pressure and so on.
The pathogenesis area of Chronic Kidney Disease caused by Diabetic Nephropath is mainly in renal glomeruli. When the toxins accumulate to some amount, renal failure and even uremia will take place.
At present, it is generally believed that Chronic Kidney Disease caused by Diabetic Nephropath has many causes including metabolism disorder, abnormal secretion, haemodynamics change and capillaries change. It is said that the coming into being of Chronic Kidney Disease caused by Diabetic Nephropath is connected with gene, insulin, glucagon, abnormal growth hormone enlarged kidney. The majority hold the idea that metabolism disorder influences the basilar, and makes their elements change. So the basilar membrane increases and the permeability of capillaries become width. In this case, Chronic Kidney Disease caused by Diabetic Nephropath comes into being.
Chronic Kidney Disease caused by Diabetic Nephropath is a common complication of Diabetes. 15% of patients with type 2 Diabetes are likely to suffer from Chronic Kidney Disease caused by Diabetic Nephropath. In recent years, more younger people tend to have Chronic Kidney Disease caused by Diabetic Nephropath. So effective treatment is necessary or else it may develop into renal failure.
At the early stage of Chronic Kidney Disease caused by Diabetic Nephropath, there is only albumin in the urine, which is latent and there is no symptoms, either. So early stage of Chronic Kidney Disease caused by Diabetic Nephropath will not lead to much influence in patients’ life. but we should know that we must treat it as soon as possible once we are diagnosed with Chronic Kidney Disease caused by Diabetic Nephropath. Some data shows that the renal failure rate for patients with Diabetes is more 17 times higher than those without Diabetes.
