How Hypertension Causes Chronic Kidney Disease (CKD)?
One of the renal functions is to filtrate the internal toxin and prevent the
exudation of protein and hemocyte. Hypertension means that blood pressure
increases, which lead to the exudation of protein. Once the protein exudates, it
will result in the damage of filter screen, which leads to the vicious circle.
If it lasts for long time, the renal compensation will increase until kidney
failure comes earlier, which can not be reversed.That’s why proteinuria(Proteinuria and Kidney Disease) is more
frightening than hematuresis.
Except keeping the blood pressure normal, patients have to pay attention to
the following points:
Change Diet habit. One has to have a good diet habit.Hypertension patients
have to have low-salt diet, less than 3g/day. But they have to not eat
high-potassium food to lower the blood pressure, for potassium can accumulate in
body due to lack of urination, which may lead to arrhythmia, even cardiac
arrest. And they should have limited high-fat food such as peanuts, fat and
soybeans etc.
One of the Causes of Chronic Kidney Disease (CKD)-- Hypertension
As Chronic Kidney Disease is not easily detected in the early stage, only 7%
Chronic Kidney Disease (CKD) patients know they have this disease. Hypertension, diabetes and metabolic
syndrome have become the main causes of Chronic Kidney Disease. In China, the
morbidity of hypertension among adults is 18.8%, its 50% among people over 65;
the percentage of hypertension patients with stage III Chronic Kidney Disease
is 30% among people over 70 in America. Compared with hypertension, hypertension
accompanied by Chronic Kidney Disease is complicated to be treated and the
disability and mortality is higher, which raises a concern home and abroad.
Hypertension patients have higher rate of Chronic Kidney Disease (CKD). The morbidity of ESRD among
Level 3 hypertension patients is 12 times than people with normal blood
pressure. The older hypertension patients are, the higher morbidity of Chronic Kidney Disease (CKD) is.
The morbidity of CKD is about 30% among people over 70, which is 2.5 times than
that among hypertension patients at the age of 60-69, 20 times than that among
people 40-59 years old, and 2-3times among people at the same age without
diabetes and hypertension. Therefore, one has to attach more importance to Chronic Kidney Disease (CKD).
Early detection is the key to do early diagnosis and treatment, which is helpful
to delay the arrival of ESRD and reduce the mortality and disability rate.
To treat it by lower the blood pressure
As the Chronic Kidney Disease caused by hypertension has relationship with
arteriosclerosis, we have to strictly control blood pressure to control the
development of arteriosclerosis. It is found in UKPDS experiment that when the
SBP>110mmHG, the rate of capillaries complication is increasing; when
SBP>125 mmHg, the risk of myocardial infarction is sustainably increasing.
The MAP has to be controlled under 100mmHg and BP under 130/80 mmHg to
effectively control the development of renal arteriosclerosis. If the protein is
>1 g/d, the blood pressure goal should be 125/75mmHg. If patients can
tolerate it, the SBP goal should be≤120 mmHg .