2014年8月21日星期四

The Treatment of Chronic Nephritis

The patients of chronic nephritis show these characteristics of dormant attacking, longer duration and slower progress. A minority of the symptoms of acute glomerulus nephritis would, after over a year’s defer continuously, be turned gradually into the chronic glomerulus nephritis.
The clinical manifestations are featured by the different degrees of proteinuria, microscopic hematuria, high pressure, edema and the damage of renal function, etc.
Owing to the fact that chronic nephritis is a disease that are not entirely identical in the transformation of the gene and pathology, so the clinical manifestations are being a quite difference. The common features for the clinical manifestations are: edema, high pressure, the symptoms of CNS, the abnormality in urine test such as proteinuria etc, the renal insufficiency, the syImmunotherapyatic manifestation(anemia, inappetence, the weakeness in the function of assimilation, malnutrition and the more accessibility of the secondary infection etc.) and the complications(hypoproteinemia, cardiac failure, the secondary infection of the respiratory tract and skin, the unbalance of water electrolyte and acidosis etc.). Except for the above common manifestations, some cases are maybe obvious in edema, and some others would have the trait of high pressure and also, there are cases with the characteristics of repeated outbreak. In clinic, these cases are classified into five types, they are ordinary type, NS type, hypertension type, mixed type and the type of repeated outbreak.
Treatment
1, General Treatment
Staying in bed is suggested for these patients with the symptoms of obvious edema, plentiful proeinuria, abundant gross or microscopic hematuria, severe high pressure, cardiac failure or for those who are generally in poor conditions.
For the patients of light edema, the less proteinuria and no notable increase in blood pressure, they are advised to get up and do some sports and the activity level could be gradually increased as appropriate.
2, Diuresis
The diuresis should be strengthened for the patients with notable edemas and the medicines used could be HCTZ, spironolactone, triamterene or furosemidum and so on(pay attention to the electrolyte balance). For the patients of hypoproteinemia, intravenous drip could be conducted for blood plasma, plasma albumin or blood substitutes.
3, Depressurization
The treatment with the medicine of depressurization should be adopted for the patients of chronic glomerulus nephritis accompanied by high pressure.
4, Glucocorticoid and Immunosuppressive Agent.
They are mainly applied into the type of chronic glomerulus nephritis and the general type with more proteinuria and could also be tried out for the type that other treatments fail to help. The taken for these medicines is not suitable or supposed to be cautious for the patients who already have the obvious symptoms of decrease in renal function.
5, Treatment with Other Pharmacotherapy
Indomethacin, as the unspecific anti-inflammatory drugs, could restrain the cohesion of the blood cells and the release of the medium of inflammation, thereby restrain the reaction process of inflammation. It could be used exclusively in general type and be used sharing with hormone in the type of nephrosis.
Dipyridamole has the effect of inhibition of platelet aggregation.
6, The Chinese traditional Treatment
By adopting the combined therapy of traditional Chinese and Western medicine, the therapeutic effect could be enhanced for the chronic nephritis. According to the treatment based on syndrome differentiation, most of the ordinary type are Qi-Yin deficiency and are suggested to improve the Qi-Yin; The majority of the nephrosis type are spleen-kidney Yang deficient and advised to Onyang Diuresis; The type of high pressure are all hepatorenal Yin deficient and should be nourished the kidney and Yin.

The chronic nephritis is with a long duration, so never in your life to seek a treatment in simple and small clinics in alleys. The burden of kidney would possibly be aggravated instead if the medicine is inappropriately used. So you’d better to take a syImmunotherapyatic treatment in a hospital.

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