As we know, PKD is a genetic disease, and develops progressively, some
patients may concurrently have polycystic liver and renal calculus. And renal
calculus may cause pain. Because of gene inherited from the parents, the
epithelial cells proliferate abnormally, yet apoptosis of this kind of cells is
inhibited. So, when proliferating to certain extent (saying the diameter exceeds
some milimeters), this proliferated part will be separated from the renal tubule
or collecting tubule, so an isolated cyst filled with liquid will form. At this
time, the phenotype of renal tubular epithelial cells changes, and renal tubular
epithelial cells turns into cyst-lining epithelial cells, which can secrete more
and more cystic fluid; however, the cystic fluid become more and more and can
not be discharged normally.
With large amount of cystic fluid accumulated, the cyst become larger and
larger, and the pressure inside the cyst also increases, which increases the
surface tension of the cyst. At this time, some sensitive patients would feel
discomfort at the lower back. Well, when infection occurs at part of cyst,
patients will feel pain. With growth of cysts, normal renal structure will be
changed by these cysts.And, glomeruli inside the kidney can selectively filtrate
red blood cells and renal tubules can concentrate the urine, reabsorb some
useful substances filtrated by glomeruli, and regulate water balance and other
electrolytes inside the body, which influences the blood volume, thus affecting
the blood pressure. So, when the glomeruli and renal tubules are damaged, their
roles can not be played perfectly, so high blood pressure, abnormality in urine
test and renal function test appear.
Since we have understood the mechanism of PKD, we will surely want to know
the therapy which can treat it effectively. Micro-Chinese Medicine is
recommended by kidney disease doctors, which in clinic also proved its
effect.
Active materials in Micro-Chinese Medicine will play roles in the surface of
the cysts, extend the blood vessels in blood walls around, accelerate the blood
circulation of the cysts wall, increase the permeability of the cyst wall,
decline the inner pressure and accelerate the reabsorption of water in cysts to
blood vessels, thus shrinking the cysts. What’ s more, Micro-Chinese Medicine
Osmotherapy can extend all levels of arteries, improve the insufficiency of
blood and oxygen in renal tissues, thus repairing the intrinsic cells thus
rebuilding renal structure and reviving renal function. after this, high blood
pressure will decline accordingly and abnormality in urine test will show
normal, pain will also disappear.