Many studies have proved that hormone could reduce albuminuria in IgAN, but they did not give direct answers that whether it could treat crescentic IgAN derived from severe pathological types.
By tracing 35 IgAN patients (91% of them have crescents), Japanese scholars found that hematuria and albuminuria disappeared after the patients had tonsillectomy and crescents had extremely decreased after repeated renipunctures. This study preliminarily demonstrated that hormones have a positive effect on treating crescentic IgA nephropathy.
In order to improve the effects of hormones, many scholars are learning the effects on the combination of hormones and cyclophosphamide. For example, some researchers found that it is effective to inhibit the formation of crescents by using 6-month hormones and oral adminstrations of cyclophosphamide to treat IgAN patients who have cresents over 20%.
However, it is not identified that which is better to treat severe crescentic IgAN patients by using hormones or combination therapy.
2. Traditional Chinese Treatment
On the basis of utilizing western meditations like hormones, cyclophosphamide, and etc., recently arisen Micro-Chinese Medicine Osmotharapy takes the priority of the protection of the kidneys to repair the impaired renal tissues, reducing the output of albumin and erythrocytes, and let albuminuria and hematuria gone. Patients would be not easy to have recurrent albuminuria and hematuria only if the renal tissues have been comprehensively repaired. The recurrences of albuminuria and hematuria would burden working load of renal tissues and continually deteriorate the disease. This would aggravate the patients’ pathological lesions. Generally, the more severe pathological leisions are, the more obvious the crescents would be.
Therefore, the major premise to protect kidney is to have negative albuminuria and hematuria(Hematuria and Kidney Disease). If we allowed albumin and blood to keep leaking, the substances our boy required could not be fully supplied and the renal damages would become more. Thus, it is necessary to turn albuminuria and hematuria negative. Hormones and cytotoxicities may be used in the early stage of the therapy. The side effects seem important in considering long-term effects.
