The recent findings show that old people who suffer from chronic disease like diabetes mellitus, elevated blood pressure and coronary disease, belongs to high risk group getting affected by nephrotoxic medications. Because old people has decreasing nephorns and they usually have renal arteriosclerosis. The function of glomerulus and tubular declines greatly, and they have a higher incidence of nephtotoxic medication than young people.
People who have below symptoms should be very prudent about the bad reaction of medicine.
1. Patients with allergy history and allergic constitution are more likely to get allergic reaction nephropathy
2. For patients with Chronic Kidney Disease, Diabetes Mellitus and primary renal damage, medication are more readily to mass up in human body, and half-life period of medicines can be postponed to dozens.
3. For patients with low blood volume, they would present shock, dehydration, and excessive urination. The content of medication in their blood and kidney increased virtually.
4.For patients with low albunimemia, their plasma protein has a lower combination ability with medicine. There is excessive free medicine in their body which imposes much burden on glomerulus.
5. Patients who take two or more medicines which can cause nephrotoxic damage to kidney simultaneously, for instance, the combination of Aminoglycosides and cephalosporins, the combination of antibiotics with renal toxicity and diuretic etc. will increase the renal toxicity of medication. Otherwise, long course of treatment and excessive dosage of antibiotic medicine are also the crucial cause of renal damage.
Therefore, patients with above conditions should keep a high alert about their body abnormality, taking proper treatment in time so that kidney damage can be controlled properly. Certainly, if you have other confusion about what medication are more likely to induce renal impairment, you can leave message on our website.
