Phlebothrombosis --the complication of Chronic Kidney Disease
Phlebothrombosis is one of the complications of CKD, which can lead to the
renal function decline.
Hypercoagulability exists in kidney for Nephrotic Syndrome patients, mainly
because the change of blood coagulation factor in blood including the increase
in fibrinogen, β-thrombus globulin and platelet and the reducing vitality of
antithrombin and antiplasmin. In this case, thrombosis easily takes place.
Antibiotic, hormone and hydragogue can aggravate the occurrence of
phlebothrombosis. If Nephrotic syndrome patients have less than 2.0g/dl plasma
albumin, the risk of phlebothrombosis increases. The Nephrotic Syndrome patients
with acute phlebothrombosis may have the symptoms such as hematuresis,
leucocyturia and urine protein, and their renal function declines. The Nephrotic
Syndrome patients with chronic phlebothrombosis have no symptom, but the renal
blood stasis often makes the proteinuria increase.
To solve the problem of phlebothrombosis, we have to apply a kind of medicine
which has little side effect. Chinese medicine is derived from natural plant
which has little side effect. Micro-Chinese Medicine may be the best choice. The
prescriptions were superfinely shattered to make the effective ingredients
released out. The most important functions of Micro-Chinese Medicine are to
dilate blood vessels and anti-coagulate, which proved effective to solve the
phlebothrombosis. In this way can the stasis be eliminated finally. Then the
renal function is restored and the patients recover in the end.
The Skin Problems of Chronic Kidney Disease(CKD) Patients
Sometimes Chronic Kidney Disease patients may have skin problems which can
haunt CKD patients all the time though it is not so severe that it threatens the
life of CKD patients. Skin disorders associated with chronic kidney disease
(CKD) can markedly affect a patient's quality of life and can negatively impact
their mental and physical health.
Uremic pruritus, which is frequently encountered in patients with CKD, is
considered to be an inflammatory Immunotherapyic disease rather than a local
skin disorder. Biomarkers of inflammation are increased in patients with uremic
pruritus and an imbalance of the endogenous opioidergic Immunotherapy might be
involved in the complex pathogenesis of the disease. Treatment options for
uremic pruritus include emollients, topical capsaicin cream, ultraviolet B
phototherapy, gabapentin, oral activated charcoal and nalfurafine, a
-opioid-receptor agonist. Calcific uremic arteriolopathy is triggered by an
imbalance of promoters and inhibitors of vascular calcification, caused by the
inflammatory changes that occur in uremia. Promising therapeutic strategies for
calcific uremic arteriolopathy include bisphosphonates and intravenous sodium
thiosulfate. Nephrogenic Immunotherapyic fibrosis is a devastating condition
associated with the use of gadolinium-based contrast agents in patients with
CKD.
At present, no therapies are available for this complication. Preventive
measures include use of iodine-based contrast agents, particularly in patients
with CKD stage 4 and 5. If gadolinium contrast is necessary, administration of
low volumes of the more stable macrocyclic ionic types of gadolinium-based
contrast agent is advocated. Hemodialysis following gadolinium exposure might
offer benefits but evidence is lacking.