1. Kidney lesion( abnormal structure or functions) for ≥3 months. There are one or a few following symptoms, no matter GFR( Glomerular Filtration Rate) falls or not: A. abnormal blood or urine; B. abnormal imaging results; C. abnormal renal biopsy.
2. GFR<60ml/min·1.73㎡ for more than 3months, whether there are the above manifestations.
The defining time of CKD is 3 months. In the first condition, because only when the kidney damage is up to certain degree, GFR begins to decrease. So it is possible that even though kidneys are damaged, GFR is normal. GFR isn’t the correct detection of kidney lesion. In the second condition, the reason why taking GFR<60ml/min·1.73㎡ as the independent standard of CKD is that when GFR is below 60ml/min, there are various complications and the prognosis is often bad.
On the basis of clinical manifestations, when Ccr(Creatinine Clearance Rate)≥60ml/min, it belongs to Chronic Kidney Disease; 15 ml/min≤Ccr≤59 ml/min, it belongs to Chronic Renal Failure or Chronic Kidney Failure; Ccr<15 ml/min, it belongs to Uremia. These classification is much clearer to make patients know their disease condition clearly.The morbidity of CKD is very high. CKD is becoming another main killer of human being.
As for the treatment of CKD, there are three treatment goals as following:
1. Controlling primary diseases.
2. Delaying worsening process of CKD
a) Control blood pressure well and blood sugar;
b) Decrease urine protein;
c) Decrease blood fat;
3. Preventing complications
Cardiovascular Disease(CVD)including controlling blood pressure andblood sugar, especially diabetes, decreasing urine protein and blood fat, no smoking, adequate dialysis, treating infection and so on. Besides the above, bettering anemia and renal bone disease as well as acid poisoning is also part of treatment of CKD.
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