IgA Nephropathy can happen to all ages, but mainly affects the young. Regardless of whether the patient is child or adult, IgA Nephropathy has different clinical manifestations and lack characteristic traits. Patients can present huge differences in term of clinical process and prognosis. Here are some common clinical manifestations of IgA Nephropathy(Iga Nephropathy Symptoms).
1. gross hematuria(Hematuria and Kidney Disease)
Thirty to fifty percent of IgA patients can present gross hematuria, which usually occurs in the aftermath of pharyngitis and tonsillitis, and it could also happen with a cold, fatigue, vaccination, pneumonia and gastroenteritis. It usually happen within 24 hours after the above incidents. Gross hematuria lasts several hours to one week, then it would remit. The length and times of hematuria would affect prognosis significantly.
2.abnormal urinalysis
Clinical manifestations include microscopic hematuria and/or proteinuria. Most patients are detected during the physical examination or check-up for other diseases. This portion of kidney patients present differential clinical manifestations and pathological changes, with varying prognosis. Some patients could present gross hematuria, as well as hypertension and renal insufficiency.
3.nephrotic syndrome
Nephrotic syndrome usually happens to patients with severe glomerular diseases. Pathologically, many glomeruli are globally obsolete or partially obsolete, with damaged foot cells, extensive tubular-interstitial damage or formation of crescents. These types of kidney patients react well to the glucocorticoids, and possess good prognosis generally.
4.acute renal insufficiency
Acute renal insufficiency is possibly related to two pathological changes. One is the formation of massive crescents within the glomeruli, and the other is the massive red blood cell casts blocking the tubules during the period of hematuria. A portion of acute renal insufficiency patients would need dialysis treatment.
5.chronic renal insufficiency
Renal insufficiency is usually the late manifestation of long-term IgA Nephropathy, with an average percentage being 20.7%.
6. high blood pressure
IgA Nephropathy patients present high blood pressure as their initial symptom, which can also happen during the course. Hypertension can also a factor which leads to undesirable prognosis.
