What is creatinine? Patients with chronic kidney disease are no doubt quite
familiar with this term and they often talk about this topic with their doctors
and friends who are suffering from chronic kidney disease as well. Creatinine is
a kind of metabolism product which should have been discharged out of the body
for it belongs to toxins just like blood urea nitrogen and urea acid. In other
words, if the creatinine accumulates in the blood for a long time or if a person
has high or increased creatinine in the blood for a long time, creatinine will
cause damage to the body, even leading to a series of complication. The normal
range of serum creatinine is 44 to 103 umol/L. When serum creatinine rises to
707 umol/L, we can get a conclusion that patients have developed into uremia
stage. In China, chronic kidney disease patients will receive dialysis to
discharge the toxins and make sure of their security. Serum creatinine of course
has become one of the most important index which can show the renal function. In
addition, the item creatinine we talk about in most of time refers to serum
creatinine, or we can also say creatinine in the blood. Creatinine can be
divided into serum creatinine and urine creatinine. In normal condition, serum
creatinine level should be lower than the one of urine creatinine.(
High Creatinine Level)
When and why does serum creatinine increase?
Generally, serum creatinine will not increase even though there has been
damage in the kidney.That’s why when some people have some discomfort and have a
blood test in the hodpital, they found that they have got uremia already. Why
does serum creatinine not increase or rise even the damage has happened in the
kidney? It is because the kidney has a strong ability of compensation.
Generally, the glomeruli in the kidney are in charge of the discharging of
toxins such as creatinine. When kidney is damaged, there will be damaged
glomeruli as well. However, other healthy or normal glomeruli will do more
filtration work to. When other glomeruli are also tired, serum creatinine will
rise or increase. Generally, when the kidney is damaged more than 50%, serum
creatinine will rise or increase. That’s why a normal person can be diagnosed
with uremia in one accidental examination.
