2014年11月25日星期二

Risk Factors for Diabetic Nephropathy

As the leading cause of end stage of Chronic Kidney Disease (CKD), Diabetic Nephropathy is mainly caused by persistent high blood glucose. Although long-term high blood sugar is the major cause of Diabetic Nephropathy, the progress of Diabetic Nephropathy can be affected by many risk factors.
★ High blood sugar.
Long-term high blood sugar is not only the major cause of Diabetic Nephropathy, but also the significant risk factor for the development of it. Therefore, if we want to prevent Diabetic Nephropathy or delay the development of it, we must have a better control about the level of blood sugar.
★ Artery Hypertension
Artery Hypertension is another risk factor for Diabetic Nephropathy and analysis of UKPDS showed that every 10mmHg reduction in systolic BP is associated with a 13% reduction in the risk of microvascular complications. Therefore, to avoid the serious complications of Diabetic Nephropathy, lowering blood pressure is very necessary.
★ Hyperlipidaemia
Among people with type Ⅱ Diabetes, high serum cholesterol is a risk factor for the progress of Diabetic Nephropathy. Among people with type ⅠDiabetic Nephropathy, increased serum triglycerides is associated with proteinuria. Seeing from this aspect, Hyperlipidaemia is another risk factor for the development of Diabetic Nephropathy.
★ Dietary factors
With damaged kidney, people suffering from Diabetic Nephropathy can not eat what they want casually as their kidneys can not bear too heavy burden. They should limit the intake of protein, potassium, salt, water and fat and so on. If they do not follow these principles, their disease will be aggravated rapidly. Therefore, dietary factors also are the risk factors for the development of Diabetic Nephropathy.
★ Genetic risk factors
A familial aggregation of Diabetic Nephropathy has been demonstrated in studies of sibling-pairs, parent-off spring pairs or studies of extended families. That is to say if one of your relatives has Diabetic Nephropathy, then you are more likely to develop Diabetic Nephropathy than others.

Apart from these mentioned above, there are some other risk factors for the development of Diabetic Nephropathy, such as smoking, drinking, staying up and overwork and so on. Aggravation of Diabetic Nephropathy will put its sufferers in danger, so it is very possible for us to avoid these risk factors. About the specific method for avoiding or prevention of these risk factors, you can leave message to me or consult our consultant online.

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