Chronic Nephritis mainly refers to the pathological change of glomerulus,
caused by many factors. The causes are unclear in most patients and have no
clear connection with streptococcus infection. The statistics showed that
only15%-20% Chronic Nephritis is derived from Acute Glomerulonephritis. As the
subclinical Acute Glomerulonephritis is not easily diagnosed, the proportion may
be higher than the number showed. Besides, as most of Chronic Nephritis patients
have no history of Acute Nephritis, many scholars believe that Chronic Nephritis
has not certain connection with Acute Nephritis and it may be caused by the
infection of various bacteria, viruses and protozoa through the course of immune
mechanism, inflammation factors and non-immune mechanism.
The diagnosis of Chronic Nephritis
The typical case is not difficult to be diagnosed, featuring the clinical
symptoms such as proteinuria, hematuresis, hypertension, edema and renal
insufficiency. And if the course is more than one year, it should be diagnosed
as Chronic Nephritis with the exception of secondary glomerulonephritis.
In diagnosis of Chronic nephritis, we should make a distinction from Chronic
Pyelonephritis, Chronic Tubulointerstitial Nephritis, Lupus Nephritis, Purpura
Nephritis and Hereditary Nephritis.
The clinical symptoms of Chronic Nephritis
The onset of most Chronic Nephritis, with the course long, is secret and it
develops slowly. Due to different pathological types, the clinical symptoms are
different, with most cases showing edema as the first symptom, severe or mild.
Some Chronic Nephritis patients just have mild edema on their face and lower
extremities while severe ones have Nephrotic Syndrome. Some patients have showed
hypertension as the first symptom and then have been diagnosed as Chronic
Nephritis. Some patients may just have proteinuria or hematuresis without any
symptoms, or diuresis and nocturnal enuresis. Some others may have no obvious
physical strength decrease until they have severe anemia or uremia as the first
symptom.
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