What Are Causes and Signs of Gout Nephropathy

In western countries and America, the morbidity rate of Gout Nephropathy is about 0.3%. According to report from European dialysis and transplant association, kidney failure which is caused by gout takes up 0.6 to 1.0% in all kidney failure. In recent years, in China, with people taking in more protein and purine in food, the rate of Gout Nephropathy increases as well. Most people with Gout Nephropathy are those who are fat, like meat and drinking alcohol.
Male patients are more than females. The average age is 45. Generally, after ten years, gout develops into Gout Nephropathy. If it can be diagnosed at an early stage and treated properly, the hyperuricemia can be controlled and renal function can be protected. A lot of urea acid is in the blood, which forms needle-shaped crystal, thus causing excessive immune reaction. In this case, pain takes place in areas such as joints of figures, feet, ankle and thumbs. Long time gout can spread to pinna. Acute gout can lead to pain, swelling, heat at night, which can even waken patients up.
Gout Nephropathy is caused by too much urea acid in the blood or difficulties in discharging of urea acid. The clinical manifestation of urea acid is such as proteinuria, edema or swelling,urinating at night, high blood pressure or hypertension, increased level of urea acid in blood and damage in renal tubules.
The causes of Gout Nephropathy:

Gout Nephropathy can be caused by primary one and secondary one. Most primary Gout Nephropathy is genetic, the way of which is not clear. More and more clinical materials indicate that Gout Nephropathy is closely related with obesity, primary high blood pressure, abnormal blood fat, diabetes and resistance to insulin. Secondary Gout Nephropathy can be called by leukemia, myeloma, wound, excessive exericise, etc.