Early kidney disease is a silent problem, like high blood pressure, and does
not have any symptoms. People may have Chronic Kidney Disease (CKD) but not know
it because they do not feel sick. A person’s glomerular filtration rate (GFR) is
a measure of how well the kidneys are filtering wastes from the blood. GFR is
estimated from a routine measurement of creatininein the blood. The result is
called the estimated GFR (eGFR).
Creatinine(High Creatinine Levels) is a waste product formed by the normal breakdown of muscle cells.
Healthy kidneys take creatinine out of the blood and put it into the urine to
leave the body. When the kidneys are not working well, creatinine builds up in
the blood.
An eGFR with a value below 60 milliliters per minute (mL/min) suggests some
kidney damage has occurred. The score means that a person’s kidneys are not
working at full strength.
Another sign of Chronic Kidney Disease (CKD)(CKD Stage 3 Symptoms and Signs) is proteinuria(Proteinuria and Kidney Disease), or protein in
the urine. Healthy kidneys take wastes out of the blood but leave protein.
Impaired kidneys may fail to separate a blood protein called albumin from the
wastes. At first, only small amounts of albumin may leak into the urine, a
condition known as microalbuminuria, a sign of failing kidney function. As
kidney function worsens, the amount of albumin and other proteins in the urine
increases, and the condition is called proteinuria. Chronic Kidney Disease (CKD)
is present when more than 30 milligrams of albumin per gram of creatinine is
excreted in urine, with or without decreased eGFR.