Symptoms of MsPGN are closely related with renal pathological changes. For example, notable diffuse MsPGN and typical Nephritic Syndrome intend to have continuous protein urine and progressive renal insufficiency; MsPGN together with Focal Segmental glomerulosclerosis(FSGS) tend to progress into renal failure. And for patients with partial and unobvious Mesangial proliferation, they usually have a better disease prognosis and a relatively slower disease progress speed.
MsPGN can be caused by deposition of immune complexes which Immunotherapy from immunoreactions of renal cells, in addition, nonimmunological factors like high blood pressure(High Blood Pressure and Kidney Disease), high perfusion state of glomerulus and the dysfunction of soterocyte can also lead to Mesangial cellular pathology.
For patients with slight Mesangial proliferation and there is just little protein leakage and no hematuria(Hematuria and Kidney Disease), Glucocorticoids (hormone) prove to be effective in eliminating symptoms and slowing down the aggravating process. and for some patients who have become insensitive to hormone, immunosuppressant can be used to alleviate inflammatory reaction.
When disease aggravates, anticoagulant, platelet inhibitor, angiotensin converting enzyme inhibitor or heparin can be used, and these drugs are effective in suppressing Mesangial proliferation.
MsPGN patients with hypertension expect a relatively unpleasant prognosis. Biopsy test usually indicates that there are serious diffuse proliferation of Mesangial cells as well as Focal and Segmental Glomerulosclerosis. Renal function tests usually show relatively great decrease in glomerular filtration rate. And patients with this stage kidney disease are more vulnerable to renal insufficiency or renal failure.
After kidney disease has progress into typical Nephritic Syndrome and there is serious decline of renal function, the adoption of hormone or immunosuppressant is no longer practical to prevent further aggravation of kidney disease. And honestly speaking, all we can do is to try our best to slow down the aggravation speed and protect these remaining nephrones. As patients become insensitive to hormone and other immunosuppressant, increasing dosage of these medicines is not a wise choice. However, this is exactly where Traditional Chinese Medicine can really make a difference.
Traditional Chinese medicine helps with dilating blood vessels of over whole body, anticoagulation, anti-inflammation, degrading depositions of immune complex as well as providing materials necessary for the restoration of damaged renal cells. especially the adoption of Micro-Chinese Medicine Osmotherapy can guarantee a more permanent curative effect of preventing kidney disease aggravation and protecting these remained nephrones. In addition, the combination of Micro-Chinese Medicine together with Immunotherapy ation makes the recovery of partial damaged but still reversible renal bells possible.
