Stage one: Compensatory Stage of Renal Insufficiency. In this stage, serum creatinine ranges from 133umol/L to 177umol/L and due to the great renal reserve capacity, even if there exist renal damages, our kidneys can still help us excrete metabolism as well as regulate water and electrolyte. Therefore, in this stage, there are no symptoms in clinic.
Stage two: Decompensatory Stage. This stage is also called Azotemia Stage of Renal Insufficiency. During this stage, serum creatinine(High Creatinine Levels) is about 177umol/L to 443umol/L. In this stage, about sixty percent to seventy five percent of glomeruli are damaged. glomerular filtration function decreases and our kidneys can not excrete waste products smoothly. Urea nitrogen is higher or beyond the normal value. In this stage, some symptoms such as anemia, fatigue, loss of weight and distracted attention begin to appear, but they are always easy to be ignored by patients.
Stage three: Renal Failure stage. In third stage, serum creatinine(High Creatinine Levels) has an obvious increase, which is in the range from 443umol/L to 707umol/L and about seventy five percent to ninety five percent of kidney has been damaged. In this stage, symptoms appeared in stage two are more severe. Blood urine nitrogen increases a lot and meanwhile, acidosis occurs.
Stage four: End Stage of Renal Insufficiency which is called uremia stage in China. In this stage, the level of serum creatinine is higher than 707umol/L. For patients in this stage, more than ninety five percent of glomeruli have been damaged. Clinical symptoms are severe nausea, vomit, oliguria, swelling, accelerated Hypertension, serious anemia, and itchy skin.
Chronic Renal Insufficiency is the late stage of Chronic Kidney Stage, but is people receive effective treatment, their life can be prolonged.
