The Glomerular Filtration Rate (GFR) of people is less than 60 ml/min/1.73 m2 for three months with or without renal damage; or people with renal damage, irrespective of the level of GFR all are regarded as having CKD. According to this standard, Chronic Kidney Disease (CKD) can be divided into five stages.
Stage one: Slightly reduce of renal function. In this stage, kidney is damaged, and GFR maybe normal or relatively high (≥90 mL/min/1.73 m2). At this time, kidney damage is defined as the most important diagnostic basis, and the relative symptom of this stage is the occurrence of high blood pressure.
Stage two: Mild decrease of GFR (60~89 mL/min/1.73 m2) accompanied by renal damage. In this stage, patients usually have high blood pressure and parathyroid hormone increase.
Stage three: Moderate decrease of GFR which usually range between 30 mL/min/1.73 m2 to 59 mL/min/1.73 m2. When this stage occurs, patients usually are accompanied by hypertension and obviously have an increase of parathyroid hormone. The absorption of calcium and spontaneous albumin decreases. Besides, renal anemia and left ventricular hypertrophy appears.
Stage four: Severe decreasing of GFR (15~29 mL/min/1.73 m2). The above symptoms become more prominent and metabolic acidosis occurs. Meanwhile potassium accumulates in the blood.
Stage five: GFR is lower than 15 mL/min/1.73 m2. Situation that people have been diagnosed with renal failure or people are receiving treatment of dialysis also indicate that Chronic Kidney Disease (CKD) has developed into the fifth stage. The signs are more severe than those in stage four, and retention of water and sodium which results from severe failure of heart occurs. Moreover, all such signs as vomit, pruritus of skin (patients have no skin disease(Skin Itching and Kidney Disease)), and decrease of appetite appear.
Chronic Kidney Disease (CKD) is a kind of recessive disease and fifth stage is the last and most serious stage, thus when found some similar signs, you’d better check your kidney in the related hospital to avoid a poor outcome. Moreover, if any questions, you can consult our experts on the internet.
