Foreign patients may not be familiar with the term uremia (end-stage renal
failure). Uremia is not an independent disease; it is a clinical syndrome of 
various kidney diseases in the end stage. As a congenital hereditary kidney 
disease, Polycystic Kidney Disease will progress gradually into the stage of 
uremia without timely and proper treatments.
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Polycystic Kidney Disease is an inborn kidney disorders in which there are 
numerous fluid-filled cysts in the renal cortical and renal medullary areas. 
They will grow large little by little and press the surrounding renal tissues 
and cause damages to the renal parenchyma. Due to long time’s lack of hypoxia 
and ischemia, the glomeruli will harden and become necrotic and the kidney 
functions will be greatly affected. As a result, the metabolic wastes and the 
toxins can’t be discharged out of the body and patients will have a series of 
symptoms. In the end, most patients will progress into the stage of uremia.How to Shrink the Cyst With Polycystic Kidney Disease(PKD) Is It Normal that PKD Patients Have Daily Nausea
Another important reason that there are so many Polycystic Kidney Disease (PKD) patients develop into uremia is delayed or inappropriate treatments. When 
the cysts are small, no special treatments are available except the symptomatic 
treatments aiming at relieving the symptoms of blood in urine, protein in urine 
and many other complications. Since these treatments can not reverse the process 
of renal fibrosis or repair damaged kidneys, the kidney functions will decline 
gradually and in the end loses its function.How Does Polycystic Kidney Disease Progress to Kidney Failure
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Since the majority of the Polycystic Kidney Disease (PKD) are related to the 
gene mutation, it is usually considered as incurable disease in the medicines 
and few researches have been devoted to it and this is the very reason why there 
is still no effective therapy in western therapies for it for a long time. In 
this regard, the Chinese medicines have obvious advantages. It can take effects 
on the cysts when they are small in size and prevent the progress of further 
kidney damages so that the illness conditions can be brought under control and 
have little probability to progress into uremia (end-stage renal failure).
Some patients may want to know whether the Chinese medicines still work for 
those that are already in the stage of uremia. The answer is positive, though 
the curative may not be so good as those in the early stage, but the medicines 
can greatly improve the patients kidney functions and length the intervals 
between the dialysis and extend the patients life span.

