Causes of Renal Anemia

Renal anemia is caused by insufficiency of hemopoietin (EPO) or the disturbance of toxin of uremic blood plasma, which influence the production and supersession of red blood cells. Renal anemia is a common complication of end stage of renal failure. The manifestations include sallow complexion, pale conjunctiva, pale and reluster lips and nails and so on.
First cause:Less hemopoietin.
1. EPO, secreted by kidneys and liver, is a kind of glycoprotein hormone stimulating differentiation and fission of precursors of red cells(PRC). Interstitial fibroblast of kidneys is the main secreting part. The decisive factor of renal fibrosis is the damage of renal intrinsic cells. Interstitial fibroblast transforms into myofibroblast, leading to glomerulosclerosis, tubulointerstitial fibrosis and sclerosis. Hereto, the producing channel of hemopoietin breaks down completely.
2. Toxin prevents bone marrow from producing blood.
In the end stage of renal fibrosis, amounts of toxin accumulated in blood restrain bone marrow producing blood, such as middle molecular substance—peptide, others like amine, phenol and so on.
3. Lack of ferride.
4. Lack of folic acid.
Second cause:Increasing damaged red blood cells causing renal anemia.
Blood plasma.
Polyamine in blood during end stage of renal fibrosis shortens life expectancy of red cells and make red cells antolysis.
Metabolic block and brittleness of red cells also reasons for antolysis.
The damaged renal cells make red cells bear mechanical damage.
Third cause:Increasing lose of red cells.
Due to the damaged filtrating function of kidneys, reabsorption function of kidney tubules breaks down and that makes part of red cells lose in urine. In addition to the lose of left red cells during hemadialysis. These factors aggravate renal anemia.
Forth cause:Hyperthyroidism.

parathyroid hormone has the functions of antagonism against EPO, restraining the formation of red cells.Meanwhile, it can increase brittleness of red cells and can shorten life expectancy. In addition that parathyroid hormone can induce marrow fibrosis and makes marrow reduce. Therefore, parathyroid hormone is closely relevant with renal anemia.

What Causes Chronic Kidney Disease?

Diabetes and high blood pressure are the two main causes of Chronic Kidney Disease and two-thirds of Chronic Kidney Disease is caused by them. Diabetes happens when blood sugar is too high, and it causes damages to many organs in your body. It may also cause damage of the kidneys and heart, as well as blood vessels, nerves and eyes. High blood pressure occurs when the pressure of blood against the walls of your blood vessels increases. If uncontrolled, or ineffectively controlled, high blood pressure can be a leading cause of heart attacks, strokes and Chronic Kidney Disease. Also, Chronic Kidney Disease can cause high blood pressure.
Some other conditions following can also affect the kidneys.
1. Glomerulonephritis, a group of diseases that cause inflammation and damage to the kidney's filtering units. These disorders are the third most common type of Chronic Kidney Disease.
2. Inherited diseases, such as Polycystic Kidney Disease, which causes large cysts to form in the kidneys and damage the surrounding tissues.
3. Malformations that occur as a baby develops in his mother's womb. For example, a narrowing may occur that prevents normal outflow of urine and causes urine to flow back up to the kidney. This causes infections and may damage the kidneys.
4. Lupus and other diseases that affect the body's immune Immunotherapy.
5. Obstructions caused by problems like kidney stones, tumors or an enlarged prostate gland in men.

6. Repeated urinary infections.

Pathological Process of Hypertensive Nephropathy

Hypertensive Nephropathy is a very common kidney disease, which is caused by Hypertension. Hypertension is one of principle causes of nephropathy. But not all patients with Hypertension will suffer from Hypertensive Nephropathy.
If internal pressure of renal blood vessels is normal with the regulating of glomerular arteriole, as well as glomerular filtration rate (GFR), Hypertension will not cause Hypertensive Nephropathy. Only long-term Hypertension commonly more than 10-15 years often induces kidney disease. Then what is the whole pathological process of Hypertension Nephropathy?
Long-term Hypertension brings "three highs" to glomeruli, that is, glomerular blood pressure, glomerular high perfusion, glomerular high filtration. The 'three highs" make blood stream flow fast in glomerular blood vessels. Persistant fast blood stream stimulates glomerular blood capillary and activates glomerular endothelial cells. The active glomerular endothelial cells consume amounts of oxygen, making glomeruli ischemia and anoxia. And then glomerular endothelial cells are damaged and appeal many inflammatory factors in blood. These inflammatory cells activate renal fibrosis.
Besides the above aspect, the inflammatory factors in glomeruli release into renal interstitium and stir up inflammatory reaction. As last, fibrosis of renal tubular epithelial cells and renal interstitium occurs.
All in all, phenotype transformation of renal intrinsic cells occurs under influence of long-term Hypertension. The damaged intrinsic cells not only appeal inflammatory factors but also secrete more extracellular matrix. These two kinds of substances both can stimulate renal fibrosis and glomerulosclerosis. Eventually, renal functions break down completely.
Therefore, aiming at the pathology of Hypertensive Nephropathy, first what patients do is to control blood pressure keeping a normal level. This can relieve the stimulation to renal blood vessels. Second, patients should receive proper and timely treatment of kidney disease to avoid worsening disease. it is quite important for patients to know that western medicines are just affect on superficial symptoms but have no any treatment effects on diseases. Only receiving western treatment can delay the pathological treatment of kidney disease , in addition to many side effects. So patients should focus on Chinese medicine treatment which is real treatment of kidney disease without any negative effects. Shijiazhuang Kidney Disease Hospital has applied Micro-Chinese Medicine Osmotherapy as the core treatment method to treat kidney disease, with Immunotherapyation and comprehensive blood purification technology as assistant treatment. This syImmunotherapyic treatment technology has proven tremendously effective in clinical practices.
First, we adopt Micro-Chinese Medicine Osmotherapy to dilating blood vessel with functions of anti-inflammation, anticoagulation, and degrading extracellular matrix. This step is to better micro renal circulation and prepare for repairing damaged cells and recovering normal renal functions.
Second, we use blood purification to clear most of toxic substances and wastes to supply a better treatment environment.
Third, Immunotherapy transplantation technology is to repair the damaged cells and rebuild the renal normal structure, recovering the renal functions.
In the whole process, we need the western medicines as the assistant treatment to control the severe clinical symptoms but as little as possible.

These four great technologies perform tremendous curative effect in treating kidney disease as a whole Immunotherapy, which occupies more and more important position in the field of kidney disease treatment. This characteristic treatment Immunotherapy has brought wellness to innumerable patients with kidney disease! If you want to know more detailed information, you can consult our online experts or send e-mail to me.

What Drugs Are Harmful to Your Kidneys?

Every drug is toxic and it passes through the kidneys after taking it. If the drugs you take are illegal substances, your kidney will be injured. So the introductions of some drugs that are harmful to kidneys are following.
1. Pain Medications
Your kidneys could be damaged if you take large amounts of over-the-counter medications, such as aspirin, acetaminophen and ibuprofen. None of these medicines should be taken daily or regularly without the doctors’ permission. Thousands of Americans have destroyed their kidneys by using excessive amounts of these medications.
2. Alcohol
Heavy drinking can hurt your kidneys because that some alcohol is assimilated by the kidneys. Alcoholics have a high risk of the happening of Chronic Kidney Disease and there are a lot of alcoholics in patients who have Chronic Kidney Disease.
3. Antibiotics
Antibiotics are dangerous if they are not taken properly. People with kidney disease need to take a smaller amount of antibiotics than people with healthy kidneys. Before you take the medicines, you must ask your doctor and get the permission.
4. Illegal Drugs

Most illegal drugs, including heroin, cocaine and ecstasy can cause various diseases like kidney disease, high blood pressure(High Blood Pressure and Kidney Disease), stroke, heart failure and even death. They can damage the kidneys and once you can’t get rid of it, your kidneys will be worse and worse.

Does Hyperuricemia Cause Uremia?

Does hyperuricemia cause Uremia? This is a hot issue patients are concerned about. At present, as a result of various reasons for Uremia, the definite diagnosis of Uremia is difficult to get, in addition to high treatment difficulty and lower survival rate. And hyperuricemia is one of main reasons for Uremia.
Does Hyperuricemia cause Uremia? Hyperuricemia is induced by long-term metabolic disorder of purine commonly among obese patients. About 20% patients with hyperuricemia suffer from renal stone. The higher concentration of uric acid, the high possibility of renal stone. Stones block ureter and cause serious waist pain and hematuria.
if hyperuricemia is accumulated in kidneys, the inflammatory actions and damages of kidneys are called as gooty nephropathy. Uric acid is stimulated in renal interstitium and kidney tubules. In interstitium there is edema and inflammatory actions which are called as interstitial nephritis. The clinical symptoms include little Proteinuria, microscopic hematuria or gross hematuria, edema, moderate hypertension and so on.
So how to treat Uremia caused by Hyperuricemia? Shijiazhuang Kidney Disease Hospital innovates Micro-Chinese Medicine Osmotherapy as core treatment with Immunotherapyation technology as assistant treatment. Through dilating blood vessels and promoting blood circulation, renal functions of patients can be recovered fundamentally. Dilated blood vessels can provide adequate oxygen and nutritions to renal cells. This step can prevent renal cells being damaged further, and recover reabsorption and filteration of renal cells. The creatinine and urea return to normal level. Uremia can be treated well. Hyperuricemia disappears.

As for whether hyperuricemia can induce Uremia, kidney specialists suggest: hyperuricemia is the early signal of kidney lesion. If hyperuricemia is not treated timely, it can cause further damage of kidneys, and even Uremia. Therefore, if there are symptoms, patients should receive early treatment and guard against worsening disease which threatens life probably.

Smoking Will Aggravate Chronic Kidney Disease

The most important function of kidneys is filtering blood to remove all kinds of harmful wastes, especially to remove creatinine and blood urea nitrogen. For patients with Chronic Kidney Disease( CKD), their kidneys are damaged; the quantity and quality of filtration decrease; the toxins cannot be removed and will build up inside the body. These toxins may hurt all kinds of organs, which will damage kidneys in turn.
Smoking is the number one preventable cause of death in most countries. It also can lead to lung disease. For patients with chronic kidney disease, their filtering functions decrease, smoke toxins cannot be removed easily and will aggravate the burden of kidneys. In addition, lung disease may affect kidneys.
Since 2003, a large number of clinical and experimental data about the adverse renal effects of smoking have been published. These more recent data together with evidence from experimental studies indicate that smoking is a relevant risk factor, which can decline renal function.
Smoking can hurt renal vessels. The more you smoke the heavier hurt your renal vessels will get. Smoking also can aggravate renal artery sclerosis, which will actuate glomerulosclerosis.
The conclusion is that smoking is an important risk factor of Chronic Kidney Disease, and nephrologists have to invest more efforts to motivate patients to stop smoking. Whether the renal function is damaged or not, people should give up smoking, especially for patients with Chronic Kidney Disease.

For detailed information, you can consult our online experts or email to me. We will provide you with professional analysis and make proper treatment suggestion for you.

The Root Causes of Chronic Kidney Disease

The root cause of Chronic Kidney Disease is damaged renal functional cells. Studies show that damaged renal functional cells are caused by the following reasons:
a. Ischemia and anoxia of renal functional cells.
Blood flow is abnormal in the status of disease. The speed is slower, which will cause the deposition of harmful wastes. And then nutrition supply cannot meet the need of all kinds of renal functional cells. It is just like that people will be hungry and be lack of nutrition if they cannot take in fresh and applicable foods. Similarly, renal functional cells will also be damaged by ischemia and anoxia.
b. Inflammatory reactions of renal functional cells.
In the status of disease, bacteria, virus, ischemia, anoxia and renal toxic substances can damage renal functional cells leading to the vibrancy of inflammatory factors.
The vibrancy of inflammatory factors can cause inflammatory reactions of renal functional cells, which will decrease renal functions and even will lead to the necrosis of renal functional cells, and then occult blood, protein and other substances may occur in the urine.
c. Blood coagulation.
Excessive blood coagulation must be increasing the difficulty of blood filtration. Overload work will damage renal functional cells.
d. Blood viscosity.
Blood viscosity is caused by the excessive lipid and saccharide. High blood viscosity can also increase the difficulty of blood filtration, which will damage renal functional cells.
e. Hyperplasia of extracellular matrixes.
Kidneys are made up of renal functional cells and extracellular matrixes. If renal functional cells are necrotic and dropped, extracellular matrixes will proliferate to take the place of the necrotic cells and squeeze other renal functional cells, which will damage renal functional cells.
All in all, under the effects of all kinds of reasons, renal functional cells will be damaged and their functions will decrease, which is called renal function decline. Once renal functional cells are damaged too seriously, the renal function may enter into the End-Stage Renal Failure.
Therefore, if you want to protect renal function, you must protect renal functional cells first. To treat Chronic Kidney Disease, the most important thing is to repair the damaged renal functional cells.
According to the reasons mentioned above, doctors in our hospital create a kind of characteristic treatment method, Immunotherapyation accompanied by Micro-Chinese Medicine Osmotherepy. Micro-Chinese Medicine Osmotherepy can dilate blood vessels, anti-inflammation, anticoagulation, prevent blood viscosity and degrade extracellular matrixes fundamentally, which provide a clean environment for Immunotherapyation.
In addition, Micro-Chinese Medicine Osmotherepy has no side effects, for it adopts external application making effective medicines permeate into kidney lesions. Clinical practices have proven that this method is effective and convenient.
Immunotherapyation has a promising future in treating Chronic Kidney Disease due to powerful vitality in repairing and regenerating all kinds of renal intrinsic cells.
Immunotherapyation accompanied by Micro-Chinese Medicine Osmotherepy can treat Chronic Kidney Disease fundamentally and has effectively improved the curative effects of our hospital.

For detailed information, you can consult our online experts or email to me. We will provide you with professional analysis and make proper treatment suggestion for you.

Classification of Chronic Kidney Disease

Chronic Kidney Disease can be divided into two types: primary Chronic Kidney Disease and Secondary Kidney Disease. Primary one includes acute or chronic Glomerular Nephritis, Progressive Glomerular Nephritis, Nephrotic Syndrome, IGA Nephropathy and so on. Secondary one includes Purpura Nephropathy, Immunotherapyic Lupus Eythematosus, Diabetic Nephropathy, Hypertensive Nephropathy and so on.
Purpura Nephropathy: Because of some sensitizers like eggs, shrimps, fishes, pollens, and so on, allergy is onset repeatedly, leading to kidney lesion.
Immunotherapyic Lupus Eythematosus: Immunotherapyic Lupus is a kind of disease which can arouse damage of multiple organs, especially kidneys. Immunotherapyic Lupus Eythematosus is a kind of self-immune diseases.
Diabetic Nephropathy: Especially for old people, it is more possible to suffer from diabetes. Duo to the higher living level, daily diet of people contains more sugar, so it is easier for people to bear diabetes. High sugar can increase blood concentration and cause high blood pressure. Long-term blood pressure can bring about problems of blood vessels. As we know, kidneys can be made up of micro blood vessels. So it is easier to bring damage to kidneys.
In the early stage of Chronic Kidney Disease, the main manifestations are Proteinuria(Proteinuria and Kidney Disease), hematuria, and so on. With more severe disease condition, some serious symptoms occurs like high creatinine, urea nitrogen. This stage of Chronic Kidney Disease is easy to worsen onto renal failure and even Uremia.

Therefore, patients with Chronic Kidney Disease should adhere to one principle that it is vital to find and treat CKD as early as possible. For the Chronic Kidney Disease, if you need other details, you can consult our online experts or send e-mail to me. there are specialized staff to serve you!

Main Reasons of Diabetic Nephropathy

Diabetic Nephropathy is one of serious complications of Diabetes, and it is one main cause of end stage of Chronic Kidney Disease(CKD). Diabetic Nephropathy is the main micro-blood vessel complication of Diabetes. Diabetic Nephropathy mainly refers to Glomerular Sclerosis, one Glomerular Lesion caused by the damage of blood vessels. There are no symptoms in the early stage.
Main Reasons of Diabetic Nephropathy
Diabetic Nephropathy occurs among patients with diabetes over ten years. Proteinuria is the obvious early symptom of Diabetic Nephropathy. According to clinical practices of dozens of years, the main reasons of Diabetic Nephropathy are as following:
1. High Blood Sugar
Poor control of blood sugar speed up the process of Diabetic Nephropathy. The increase of blood sugar and glycosylation wastes arouses proliferation of mesangial cells, more extracellular matrix, expansion of mesangial membrane, incrassation of basilar membrane.
2. Abnormal blood flowing condition of kidneys
a) IV Collagen of glomeruli makes basilar membrane thicker leading to diffusive and segmental mesangial lesion. As a result, it causes Glomerular Sclerosis.
b) When there are too much blood sugar, high perfusion, high filtration and crossing high pressure of blood capillary enlarge the mesangial cells and arouse the foot fusion of epithelial cells, leading to the drop of epithelial cells from basilar membrane.
c) Due to high blood pressure, more proteins leak out of blood and accumulate in mesangial area and renal basilar membrane, leading to matrix proliferation and diffusive Glomerular Sclerosis.
3. Hypertension(High Blood Pressure and Kidney Disease)
Hypertension is not relevant with Diabetic Nephropathy directly. But primary Hypertension and high blood pressure during the treatment can speed up the worsening process of Diabetic Nephropathy, so as to more protein leaking out of blood.
4. Inherited Factors
Most patients with Diabetes don’t suffer from Chronic Kidney Disease, but some patients who control blood sugar well stand Diabetic Nephropathy. Besides that, the incidence of Diabetic Nephropathy shows the familial aggregation. Meanwhile, the incidence in different races are various. All these show that the occurrence of Diabetic Nephropathy is related to inherited factors.

Due to insufficiency of Diabetes absolutely or relatively caused by different reasons, the metabolism of sugar, protein and fat is obstructed, leading to the main symptom of Chronic Blood Sugar. Diabetes can cause damage to the whole kidneys. Patients with Diabetic Nephropathy find continuous Proteinuria, they should take timely proper treatment to avoid the end stage of Chronic Kidney Disease—Uremia.

Prevention of Chronic Kidney Disease

Chronic Kidney Disease (CKD) is a progressive loss in renal function over a period of months or years. As there is no obvious symptoms in the early stage, Chronic Kidney Disease may seem to have come on suddenly, but it usually has lasted for a long time before you realize it. CKD may sometimes be prevented by controlling the other diseases or factors that can cause kidney disease.
A variety of factors could contribute to Chronic Kidney Disease. You may be unable to change some main risk factors, such as age, race, being male, family history, while some other factors could be controlled, such as Hypertension and Diabetes. Keeping your blood pressure and blood sugar levels near normal is helpful to prevent your renal pathological changes.
The sooner you change the controllable factors that damage your kidneys, the better. The following instructions could help patients with Chronic Kidney Disease prevent or slow down the progression of kidney damage.
Firstly, keep normal blood sugar. A persistently high blood sugar level can damage blood vessels in the kidneys. If you have Diabetes, you should strive to keep your blood sugar as close to normal as possible. Besides, talk to your doctor about how often to check your blood sugar.
Secondly, keep your blood pressure below 130/80. High blood pressure(High Blood Pressure and Kidney Disease)  gradually damages the tiny blood vessels in the kidneys. You are required to check your blood pressure at home regularly.
Thirdly, maintain healthy levels of lipids. Eating some food that is low in protein and fat may reduce your risk for kidney disease. Therefore, you need to pay attention to your daily diet.
Fourthly, stay at a healthy weight. This can help you prevent other diseases, such as diabetes, high blood pressure, and heart disease.
Fifthly, do not smoke or use other tobacco products. Smoking can reduce blood flow and increase blood pressure. In order to keep healthy, it is essential to quit smoking.
Lastly, avoid long-term use of medicines that can cause damage to the kidneys, such as pain relievers called NSAIDS and certain antibiotics.

If you have any questions about Chronic Kidney Disease, you are free to consult our online experts or email to me. We can provide you more detailed information and professional analysis.

Treatment for Chronic Kidney Disease(CKD)

As we know, there are many inducements which can cause Chronic Kidney Disease (CKD), say medication poisoning, excessive drinking and smoking and bad mental status. And the direct consequence of these inducements are those inherent cells in kidneys get damaged differently. If no treatment or treated improperly, the original renal structure get changed and kidneys will fail to work properly. Therefore, we should master some precautions to prevent the progression of Chronic Kidney Disease.
To avoid the aggravation of Chronic Kidney Disease, we can adopt measures in different stage. What you should do when there is no obvious symptoms? Because of good compensatory ability of kidneys, you would have no obvious symptoms in early stage,. When your GFR is more than 60%, you would present light edema, fatigue. You should pay more attention to your diet, low protein, low phosphorus, low potassium. Meanwhile, you should control the primary disease like acute/chronic glomerulonephritis, Lupus Nephritis, Purpura Nephritis, or other kidney diseases
In case that your condition have deteriorated unexpectedly and your GFR has been less than 50%, you can still do something to slow down its aggravation. The prevention of this stage may start from three aspects: daily life, diet and prevention of infection. When the disease occurs, patients with Chronic Kidney Disease(CKD) should stay in bed, especially those who have severe swelling, because good rest could help to avoid complications of Hypertension and Heart Failure. However, in the stage of recovery, patients should do some mild exercises properly so that the muscles could return to normal gradually. Besides, more attention should be paid to the weather for it may aggravate the disease.
At last but not least, no matter whether you are a patient with Chronic Kidney Disease or not, you should have a correct cognition to health care. Good mental status, healthy life habit and regular check-up are very helpful to prevent and monitor your body condition. Even though you have noted you have problem in you health, you need calm down at first and choose correct treatment rather than take medication blindly. Especially for Chronic Kidney Disease, you need to restore those inherent cells. As long as these inherent cells get recovered, your symptoms can disappear spontaneously.

If you have any confusion, you can consult our experts online about your condition. Also, if you are reluctant to talk here, You can send your medical reports to me, our medical staff will help you analyze your condition and give you a reply.

Bad Habits Leading to Chronic Kidney Disease (CKD)

Why does the incidence of Chronic Kidney Disease (CKD) remain high, no matter how much attention people pay to nutrition and health? Experts point out that CKD is caused by many factors especiallypeople’s lifestyle. Thus what are the bad habits affecting the renal function?
■ Holding urine frequently.
If the urine stays for a long time in the bladder, bacteria can breed and retrograde to the kidney via ureter, leading to urinary tract infection and Pyelonephritis. The process appears repeatedly can induce CKD which is not easy to be cured.
■ Taking medicine abusively or excessively
Taking too much medicine with Nephrotoxicity may easily cause renal tubular interstitial damage because some elements in them can damage the kidneys. For instance, Chinese herbal medicine with aristolochic acid which is contained in Caulis aristolochiae manshuriensis (guan mu tong), Aristolochia fangchi (guang fang ji), dutchmanspipe root (qing mu xiang); Non-Steroidal Anti-inflammatory Drugs (NSAIDS) and antibiotics in medicines such as somiton, paracetamol.
■ Staying up, having salty food, and drinking little or no water in a whole day
It is easy to have damage to renal function for those people who are always stay up late, suffer great pressure, and love strong tea and coffee.
If one has a habit of loving salty food, he/she is likely to have a high blood pressure which can lead to the abnormal of blood flow in kidneys.
Lacking water is the direct reason of less urine. And then the concentration of wastes and toxin in urine will increase and cause renal diseases such as Renal Calculus, Hydronephrosis.
■ Having too much seafood and drinking beer
Amounts of food with high-protein(Proteinuria and Kidney Disease), such as fish and meat, is the origin of extensive metabolic waste including Uric Acid (UA) and urea nitrogen, all of which can make the renal burden of excretion heavier.
Further more, Hyperuricemia may be a consequence of too much drinking which can also lead to other metabolic diseases including Hyperlipidemia, and kidney disease. And in summer, many people would like to have seafood and to drink wine at the same time which lifestyle has been once called “the most harmful diet to kidneys” by the doctors of renal disease.
The tips mentioned above are the habits which injury the kidneys most. So people must form a good habit in daily life in order to stay far away from diseases.

If you want to know more information, please send an email to me, you will get a satisfying answer.

What Would Cause Chronic Kidney Disease in Daily Life?

Many patients are suffering from chronic kidney disease. But they do not know why they get such a disease. By tracking their illness history, there are some prevalent reasons as below:
Firstly, patients with chronic kidney disease (hereinafter called CKD) usually have an elevation in plasma viscosity, blood viscosity, and the content of fibrin and the aggregation of thrombocyte get revved up. These phenomena are the main reason to trigger ischemia and necrosis.
Secondly, patients once had pulmonary Infections such as Pharyngitis, Tonsillitis and other streptococcus infections. Clinical cases reflects that these disease can trigger more infection in renal area, which aggravate chronic kidney disease.
Thirdly, long-term suppressing urine not only damages bladder, but urine retention in bladder can facilitate bacteria reproduction. Once these bacteria go backward to ureter or kidney, these toxic substances can infect kidney so that urinary infection, kidney disease and even uremia emerge.
Fourthly, there are numerous Chronic Kidney Disease(CKD) cases which are caused by taking medicine blindly. Many medicines for treating cold and defeating inflammation, pain-killer, diet pill and Chinese herbal medicine belongs to nephrotoxic medicines. However, patients have no enough knowledge about these medication and they still use this widely.
Fifthly, Kidney is more likely to happen if excessive salt are absorbed. The main content of salt is Nacl. As we know, Na+ is an essential mineral for human body, and Cl- is necessary to produce gastric acid and sustain blood osmotic pressure of human body. However, excessive Na+ can make water retention in human body so that edema takes place. Moreover it can increase blood volume and small arteries tension so that elevated blood pressure occurs in patients. Therefore, people who takes more salt is more likely to have a high incidence of hypertension. Hypertension is readily to cause Nephrology.

Therefore, no matter whether we suffer from chronic kidney disease or not, we should pay close attention these aspects in our daily life. Meanwhile, we should take active treatment once we have present discomforts like edema, high blood pressure, fatigue, anemia, vomit and nausea, frequent urination and etc.

The causes for Chronic Kidney Disease in Women

In A Dream in Red Mansions (The Story of the Stone) witten by Cao Xueqin, Jia Baoyu says that women are made from water. This is a good comparison which not only shows that women are as beautiful as water, but also tells us that women are weak and easy to get diseases. Then what are the specific reasons for women to get Chronic Kidney Disease(CKD)?
I. Women have poor immunity compared with men.
Because of this, there may cause some immunologic diseases in women such as Immunotherapyic Lupus Erythematosus (SLE), Dermatomyositis. In addition, they are the group of people who are easy to get cold and infection and as such, which are inducing factors of Chronic Kidney Disease (CKD).
II. White-collar women are easy to get CKD due to their work environment.
White-collar women have to stay in an airtight room with air-condition, which will lead the decrease of their immunity little by little. Because in such an environment, the harmful elements in the air are too much, such as carbon dioxide, toxic dust, each of them is capable to lead kinds of diseases including CKD.
III. Sentimentality is harmful to kidneys.
Young women in modern society have to suffer great pressure from many aspects, such as relationships in colleagues, work burden, and their emotion problems. Different from men, women are always of sentimentality and are easy to be hurt by these problems. As long-term depressed mood can make the body secretes kinds of toxins, especially in those with poor immunity, women are in high risk of getting diseases. And if timely treatment has not been given, the disease may develop into CKD.
IV. Taking too much health care products may also cause renal disease.
Too much health care products with high-protein and nutritions can increase the burden of kidneys and sometimes cause proteinuria(Proteinuria and Kidney Disease); this is the so called overnutritio. As for the CKD sufferers, their proteinuria may be aggravated.
V. Infection commonly occurs among women.
As women have a broad and straight urethra which directly connect with the bladder, the occurrence of Cystitis and Urethritis is very high, leading to Nephritis which is an omen for Chronic Kidney Disease. According to this, women are of high risk of CKD.

These are the five factors which can cause Chronic kidney disease without any sign. People can always avoid the disease if they form healthy habits in their daily life, for example, open the window frequently to have fresh air, drink enough water every day, pay attention to the elements in health care products, and keep in a steady mood. Thus we can do our best to stay far away from any kinds of diseases including kidney disease, and live a long healthy life.

Office Ladies, Take Good Care of Your Kidneys!

Office ladies are at higher risk of getting Chronic Kidney Disease. Women tend to be hurt by such inflammations as Cystitis and Urethritis, because they have wider and shorter urethra which is linked to bladder directly. If those diseases cannot be controlled well, the inflammation may spread backwards to cause Nephritis. Office ladies who have mild lumbago and long-term urinary tract infection need to watch out for the Silent Killer--- Chronic Kidney Disease. Since there is no obvious symptoms at first, Chronic Kidney Disease cannot be noticed timely. Also, it always takes a long period to develop, so Chronic Kidney Disease is easily to be neglected.
How does office lady get Chronic Kidney Disease? The keywords in answering this question are sentimentality and life style.
Nowadays, women have great pressure of work and competition, and office ladies are the first to be affected. All the youngsters will easily have a poor temper and be impetuous, and women are so sentimental, so young women are more likely to have unstable emotions. When women are under gloomy affections for a long time, their immunity will be hurt, and kidney diseases will be the victim of poor immunity.
In addition, office ladies always sit in an airless room only with air condition. Harmful substances such as excessive carbon dioxide and poisonous dusts will accumulate in the air and lead to the decrease of body immunity and the problems of some organs. If this condition lasts for a long time, poor immunity may lead to infections or some other lesions in kidney, so Nephritis may occur. Also, office ladies always enjoy fast food which has improper structure of nutrition and excessive calories, so too much calories accumulate in kidneys, resulting in the decrease of immunity as well.
Office ladies, how to protect your kidneys? Here are some tips for you.
First, avoid catching a cold, because cold will induce or aggravate kidney diseases.
Second, open the windows frequently and drink more water.
Third, have more cool and refreshing food (such as honeysuckle, green beans, Chinese yam, Semen Euryales, cassia seed, fish soup).
Fourth, don’t be overtired. Those women who are under great pressure should alternate their work with rest wittingly.
Fifth, pay more attention to the cultivation of emotion to avoid sharp changes of emotion and to solve the problems in life timely.
Once you have discomfortable feelings in your low back, or you have malaise like excessive thirst, frequent urination, pale complexion, blurred vision and fatigue, you should consult doctors in time to prevent your kidney from being hurt.

If you have any question, you can leave a message to me or talk with our experts online.

What Reasons can Lead to Acute Exacerbation of CKD?

Chronic Kidney Disease (CKD) always has a long process to go from its early stage to end stage. Some people may keep the disease under control for decades, which means the patients can live a normal life in some degree. However, Chronic Kidney Disease may be exacerbated quickly, and develop into Chronic Renal Failure in a short period of time if there are external factors invading the inner environment of the body.
Here are some factors which should be noticed by the patients with Chronic Kidney Disease.
Infection of bacteria and virus.
This is the most common reason of the acute exacerbation of Chronic Kidney Disease (CKD), because many kinds of ailments can not always be avoided in daily life, which includes cold, flu, pharyngitis, tracheobronchitis, and asymptomatic bacteriuria.
Overstrain.
Patients with Chronic Kidney Disease are suggested to keep relaxed and easy so that the environment in their body can be steady. Overstrain such as strenuous exercise, hard physical labor, and sexual strain, can easily lead to acute exacerbation of Chronic Kidney Disease (CKD).
Taking medicines of renal toxicity.
The kidneys are sensitive to some medicines, because their main functions are excreting the wastes and reabsorbing the effective elements of the body, which can be decreased by the medicines with renal toxicity. These medicines are various and should be taken under the instruction of doctors, such as gentamicin, and kanamycin.
Acute stimulation.
This mainly refers to some emergency conditions which will overburden the body, such as acute gastrointestinal bleeding, serious gastroenteritis, nausea and vomiting, and diarrhea. Chronic Kidney Disease (CKD) can develop into renal failure with the stimulation of these diseases.
Other factors. This part includes factors such as the imbalance of fluid and electrolyte, and acid-base disorder.

Only when the patients with Chronic Kidney Disease take care of their daily life and try to avoid these factors can they do a better job in controlling the CKD in its early stage.

How does Diabetes Cause Chronic Kidney Disease

We all know that Chronic Kidney Disease can be caused by many reasons and Diabetes is one of the most common causes. Meanwhile, do you know how Diabetes causes Chronic Kidney Disease? Before talking about it, firstly, let us learn what Diabetes is.
Diabetes means an accumulation of excessive glucose in blood. It is caused by body’s failure in producing insulin or insulin resistance, a condition in which cells fail to use insulin properly, sometimes combined with an absolute insulin deficiency. Diabetes itself does not cause death; however, its complications such as cardiovascular disease, retinal disease and kidney disease can push people into a very dangerous situation. Thereby, Diabetes is called “silent killer” in some countries. The most outstanding characteristic of Diabetes is high blood sugar. Blood sugar has a close relationship with the happening of Diabetic Nephropathy, so if we can not control our blood sugar level well, it will accelerate the development of Diabetic Nephropathy.
Diabetic Nephropathy is a kind of Chronic Kidney Disease and the formation of it is long and complicated. When people get Diabetes, the long term and excessive high blood sugar will increase capillary permeability which will cause the exosmosis of plasma protein. When the leakage of plasma protein develops to a certain degree, capillary basement membrane will be damaged. Gradually, glomerulosclerosis and renal atrophy will appear among patients. Thereby, a better control of blood sugar has a great significance for patients with Diabetes.
Chronic Kidney Disease can be caused in different ways, and Diabetes is one of them. Thereby, in our daily life, we should try to maintain a healthy weight by doing some moderate physical exercises to prevent Diabetes. For patients with Diabetes, they should keep a close eye to their blood sugar. Once finding blood sugar increase, they should take some measures to decrease their blood sugar gradually, not in a sudden. Meanwhile, patients with Diabetes should also prevent the happening of diabetic complications through some ways, for example, keeping healthy living habits, and doing physical examinations frequently.

For western people, they are easier to get Diabetes, because they like eating sweet foods. Thereby, they should pay more attention to their blood sugar and take random blood sugar test regularly.

How does Chronic Kidney Disease Cause High Blood Pressure

Hypertension is common in our daily life, and its most obvious characteristic is high blood pressure. Most of people know that high blood pressure can cause Chronic Kidney Disease, but they do not know Chronic Kidney Disease can also cause high blood pressure. High blood pressure is one of symptoms of Chronic Kidney Disease, and then do you know how Chronic Kidney Disease causes it?
Chronic Kidney Disease affects blood pressure in different ways. The following are the three kinds of pathogenesis causing high blood pressure through Chronic Kidney Disease.
■ when people get Chronic Kidney Disease, injury of renal parenchyma will appear, leading to the reducing of prostaglandin. Prostaglandin is secreted by renal tissues and it aims at lowering blood pressure, so its reducing will result in the increase of blood pressure.
■ The root reasons of Chronic Kidney Disease are renal ischemia and anoxia. Renal ischemia can cause constantly increase of renin which is secreted by juxtaglomerular cells. The main function of renin is to activate proangiotensin and then makes it turn into type Ⅰ angiotensin. Through tissular invertase, type Ⅰ angiotension is converted into type Ⅱ angiotension. Type Ⅱ angiotension has a strong ability of shrinking blood vessels, which will cause an increase of blood pressure.
■ when renal function is damaged, waste products and toxins can not be excreted fluently. Accumulation of these wastes will reduce blood circulation, leading to the increase of blood pressure. The long term duration of renal Hypertension causes arteriosclerosis which will aggravate kidney disease.
Blood pressure has a great influence on the severity of Chronic Kidney Disease. The degree and duration of high blood pressure(High Blood Pressure and Kidney Disease) usually are the typical signs of severity and prognosis of Chronic Kidney Disease. Generally speaking, the longer the high blood pressure maintains, the more serious the Chronic Kidney Disease is and meanwhile, the worse the prognosis is.

Chronic Kidney Disease can cause high blood pressure. Inversely, high blood pressure also results in Chronic Kidney Disease. Thereby, even for us normal people, we should pay close attention to our blood pressure. We should do blood pressure test regularly, so as to avoid the formation of Chronic Kidney Disease.

Obesity Causes Chronic Kidney Disease

People will always wonder how they get Chronic Kidney Disease. Kidneys can’t beat as a heart, and will not have distending pain as a stomach,so they play the part of street sweeper in human body and bear the burden of hard works silently. Therefore, when there are symptoms and kidney diseases are detected, the diseases have already been the Chronic Kidney Disease and in the late period. Among all the inducing agents, obesity is very common in the modern society. There are mainly four diseases that can easily arouse kidney diseases, and all the four have relationship with excessive fat in human body.
★ Hypertension. Corpulent people can easily get Hypertension. When blood pressure rises, blood vessels in kidneys must bear higher pressure. A rubber band will lose its elasticity if it is tightly strained for a long time, and so will blood vessels. If the blood pressure is high for rather long time, those vessels must be sclerosed, and the kidney which is made up of numerous blood vessels will be sclerosed thereby.
★ Hyperlipoidemia. Kidney lesions aroused by obesity are mainly caused by the accumulation of fat in kidneys, and the weight and size of kidney will arise. Obvious fat accumulation in renal tubules and glomeruli can be detected in histological examination, so Focal Segmental Glomerulosclerosis will appear. Besides, people with Hyperlipoidemia may have Atherosclerosis which is like cream in the blood walls and it will result in glomerulosclerosis as well.
★ Diabetes Mellitus. Overweight people are likely to have insulin reaction and Diabetes Mellitus. The morbidity will rise with ages. Women with much fat will easily be attacked by Diabetes and have symptoms as excessive thirsty, appetite and urine in an unobvious way. Kidney lesion is one of the main complications of Diabetes. Proteinuria will appear in the early period, and it will become more and more in the late period, leading to renal insufficiency and even Uremia.
★ Hyperuricemia. Hyperuricemia is a disease caused by long-time disordered purine metabolism, and it is very common among people with adiposity. About 85% of the Hyperuricemia sufferers have kidney diseases after the age of 30, and it will be Chronic Kidney Disease or even Chronic Renal Failure some years later, threatening the life.

Nowadays people tend to have food with more fat and calories, and have less exercise in the daily life because of busy work. However, obesity dose lead to many diseases in many cases, so that every one should keep a healthy lifestyle to avoid Chronic Kidney Diseaseas well as many other possible diseases caused by overweight. If you want to know more about Chronic Kidney Disease, you can talk with the consultants online or leave a message to me.

What Makes You Get Chronic Kidney Disease

As we know, Chronic Kidney Disease is hard to treat, so nobody wants to get Chronic Kidney Disease. If we want to avoid this disease, we should know well about its causes. The followings are the general introduction about causes of Chronic Kidney Disease. .
Ⅰ. Some researches show that obvious increase of plasma viscosity, whole blood viscosity, content of fibrin, and hematoblastic coherence can usually be seen among patients with Chronic Kidney Disease. And these are important causes of renal ischemia and renal necrosis.
Ⅱ. Infection is one of the inducements of Chronic Kidney Disease. Pharyngitis and amygdalitis can lead to Chronic Kidney Disease. Cold is one of the common causes that triggering and aggravating Chronic Kidney Disease.
Ⅲ. Some factors come from terrible environment such as cold and moist will reduce people’s immunity and body resistance.
Ⅳ. Overstrain also decrease people’s immunity. And long-term overstrain will increase the morbidity of Chronic Kidney Disease.
Ⅴ. Long-term suppression of urine is another reason of Chronic Kidney Disease. Long-term suppression of urine in bladder can cause the heavy reproduction of bacterium. When urine reflows to ureter and kidney, these toxic substances will result in renal infection, so as to cause kidney disease. Moreover, Long-term suppression of urine not only causes chronic kidney disease, but also causes urinary tract infection as well as damage to bladder.
Ⅵ. Chronic Kidney Disease caused by the abuse of medicines is common. Some familiar medicines such as patulin, anti-inflammatory painkillers and diet pill may cause renal damage. Thereby, we should not take medicines without guidance of doctors in our daily life.
Ⅶ. Chronic Kidney Disease can result from the bad control of some diseases such as Diabetes and Hypertension. For patients with Diabetes, if their blood sugar can not be controlled well, there will be a high incidence of Diabetic Nephropathy. It is similar to patients with Hypertension, if their blood pressure can not be kept in a low level, they will be likely to get Hypertensive Nephropathy.

There are so many reasons for people to get Chronic Kidney Disease; however, if we can take some effective preventive measures, Chronic Kidney Disease will be far away from us.

Common Causes of Chronic Kidney Disease

As its name implies, Chronic Kidney Disease (CKD) means renal damage which has existed for more than three months. Renal damage can be caused by various diseases and the most common three are Diabetes, Hypertension and Glomerulonephritis.
◆ Diabetes causes Chronic Kidney Disease (CKD)
Diabetes can cause Diabetic Nephropathy which is a common Chronic Kidney Disease. Diabetic Nephropathy is one of the most serious complications of Diabetes and it mainly refers to the diabetic glomerulosclerosis.
Diabetes means the high blood sugar in the body, which results from the insufficiency of insulin or the non-response of cells to insulin. Long-term high blood sugar can cause an increase of capillary permeability, leading to the exosmosis of plasma protein. The serious exosmosis of plasma protein will damage the basement membrane of capillary permeability, which will lead to glomerulosclerosis and renal atrophy.
◆ Hypertension causes Chronic Kidney Disease (CKD) (High Blood Pressure and Kidney Disease)
Hypertension can cause Hypertensive Nephropathy, and this usually happens to patients who have Hypertension for more than five to ten years. Our kidneys can filter out waste products and at the same time prevent the leakage of protein. When blood pressure increases, protein will be filtered out. Long-term leakage of protein will damage our kidney, and when renal damage can not be cured within three months, Hypertension will develop into Hypertensive Nephropathy which is a common Chronic Kidney Disease.
◆ Glomerulonephritis causes CKD
Glomerulonephritis, also known as Glomerular Nephritis, is a renal disease characterized by inflammation of the glomeruli, or blood vessels in kidney. It may present as chronic renal failure. In the early stage of Glomerulonephritis, there are no obvious symptoms, so patients with this disease are likely to miss the optimal time for receiving treatment, leading to development of renal fibrosis.

The above are the common three causes of Chronic Kidney Disease. Causes of Chronic Kidney Disease are various, so in our daily life, we should keep healthy living habits, so that we can avoid harming our kidneys.

Is Hypertension a Cause for Chronic Kidney Disease

When the patients with Hypertension have clinical manifestations of Chronic Kidney Disease such as proteinuria, red blood cells in the urine, nocturia, increase of the urea nitrogen and serum creatinine, they should pay more attention to the functions of their kidneys.
At the early stage of Hypertension, almost all the arterioles of the body will get spasmic, so does the renal arterioles. However, the kidneys are not at a high risk during this process since the condition can be remitted in a short time, as long as timely treatment can be given. With the aggravation of the high blood pressure, the arteriosclerosis also can be sharpened as well as the renal arteries, thus chronic kidney disease is formed.
Hypertension can cause chronic kidney disease directly which is called Hypertensive Nephropathy. The disease can be benign or malignant arteriolonephrosclerosis with a different influence to the kidneys.
※ The benign arteriolonephrosclerosis refers to the hyaline change of renal arterioles which is a consequence of long-term Hypertension, and its degree closely relates to the time of the high blood pressure(High Blood Pressure and Kidney Disease) and the degree of it. Bit by bit, ischemia may appear in the kidneys and the functions of glomeruli and the renal tubules decrease.
When the kidneys are lacking blood, they will secrete a kind of substance called rennin which can reactivate angiotensin and shrink all the vessels of the body, thus increasing the blood pressure. A high blood pressure is helpful to the improving of the blood volume in some organs and tissues for a short while, but it also can arouse the arteriosclerosis in the kidneys, and then aggravates the ischemia mentioned above. In this way, high blood pressure and renal damage form a vicious circle which can do much harm to our body.
※ The malignant arteriolonephrosclerosis particularly refers to the diffuse changes of glomeruli which is caused by the acute kidney disease. It is symbolized by the quick aggravation of the disease and a sudden decrease of the renal function.

A majority of the patients with Hypertension can get kidney disease at their late years, and only 10% of them will be free from this mirotic. In addition, both the kidney disease and high blood pressure can be severer with age growing.

How does the Children Nephritis Turns into Chronic Kidney Disease?

Children Nephritis can change into Chronic Kidney Disease (CKD) with the influence of some factors, such as the physical conditions of the children, the kinds of the Nephritis and the treatment being taken.
I. The internal environment of the children.
As we know, the immune Immunotherapy of children is easy to be injured if they have some diseases. Their physical condition will also be weak after getting Nephritis, and if they catch some illness during this process, they are at high risk to get a recurrence of hematuria(Hematuria and Kidney Disease) and proteinuria(Proteinuria and Kidney Disease). Children will get CKD if this process came over and over.
In addition, some diseases caused by streptococcus including amygdalitis, pharyngitis and scarlatina are factors which can lead to acute kidney disease.
II. Different kinds of Nephritis.
▼Acute Glomerular Nephritis often occurs in a very short time with a good treating effect and is not easy to reoccur.
▼Lingering Glomerulonephritis refers to the process in which the Acute Glomerular Nephritis will last for six months or more than one year after being treated. Generally speaking, it will not cause renal insufficiency or high blood pressure.
▼Chronic Glomerulonephritis can be a consequence of Acute Glomerular Nephritis, or a complication of a kind of disease in a slow way. This is a main factor which can develop into CKD and it is difficult to be controlled only by the western medicine.
▼Rapidly Progressive Glomerulonephritis attacks the children with a sharp decrease of the renal function. The children may have some severe symptoms of kidney disease and be a sufferer of renal failure in several weeks or months.
III. The time of treating is also very important.
▼At the beginning stage of the disease, the immune complex deposit in different intrinsic cells and cause various inflammatory responses by excreting inflammatory factors. The intrinsic cells will be damaged during this process and leads to obstacles of the micro-circulation which is a blasting fuse of proteinuria and hematuria. A timely treatment at this time can stop the step of CKD since the disease is only caused by the damage in cells.
▼ If CKD is not controlled well in the first stage, it gets into the second stage called the forming stage of renal fibrosis. In this stage, a mass of extracellular matrix (ECM) deposit in the mesangial area, and they can replace the intrinsic cells of the kidneys little by little, finally causing glomerular sclerosis and shrink of the renal tubules. It is difficult to control the disease at this stage, however, if proper treatment can be given, it is possible to control CKD to keep in a stable condition.
▼Scarring stage is the end stage of Chronic Kidney Disease(CKD) in which the children are in a former stage of uremia. What they should do is far more less than the former two stages, at this period, the children should keep a good mood and try to find some good treating methods, and it is good for them to do more exercises.

Finding CKD in a child is really a miserable thing to the whole family, but it doesn't mean that we should give up and stop the love of life. Actually there are a lot of things we can do to help. Do not be frustrated and just cheer up, have a talk with the consultant and they can tell you what you can do next.

Can Smoking Arouse Chronic Kidney Disease

It is wildly known that smoking is harmful to the lung and heart vessels which can cause cancer in lung or cardiovascular disease. However, how many people have the knowledge that smoking can also do harm to our kidneys and cause Chronic Kidney Diseases?
More than 4,000 noxious chemical compound produced by each cigarette is likely to enter the lung and then to be one part of the blood circulation. As we know, kidneys should filter and excrete the wastes of the body, so the aromatic amines (tar for instance) and acrolein in the cigarette also should be expelled out of the body via kidneys, during which, the kidneys will be damaged a lot.
◆ Being the main cause of craving of tobacco, nicotine in the cigarette (0.5-2.7 mg/cigarette) is a kind of strong excitant which can stimulate the nervous centralis and refresh oneself. Meanwhile, nicotine can help to increase the heart rate as well as the blood pressure, and then leading to cardiovascular disease. The blood coagulation leaded by it is a reason for the blocking of the vessels which can decrease the blood volume in the kidneys and exacerbate Chronic Kidney Diseases.
◆ In addition, the carbon monoxide (CO) in the cigarette (400ppm/per cigarette) is a kind of toxin which can interfere the exchange of the oxygen without color and smell, and it can also impede the combination of the oxygen and protoheme by resulting in anoxia in the body. In a normal person, the CO in the blood should be less than 1%, but that in a smoker may be as high as 15%. If this condition lasts for long, the blood can be blocked and influence the mind and our judgment; further more, the accumulation of the fat makes the renal burden heavier than before.

◆A long-term smoking makes the blood pressure changeable, and the blood vessels uptight, which can broke the Immunotherapy microcirculation gradually. As for the patients with kidney disease, smoking is not only a destroyer of the blood circulation and oxygen supply, but also a causer of cancer, includes Renal Cell Carcinoma, Transitional Cell Carcinoma, Carcinoma of Urinary Bladder. Smoking is closely related to the data of renal damage, especially the decrease of GFR and appearance of proteinuria. That is why the patients with Chronic Kidney Disease should be more cautious if they are smokers.

Metabolic Disturbance Causes Chronic Kidney Disease

High blood pressure, high blood sugar, Hyperlipaemia and high blood uric acid all can indicate that there is metabolic disturbance in human body. Metabolic disturbance can cause renal damage, leading to the occurrence of Chronic Kidney Disease.
● High Blood Pressure(High Blood Pressure and Kidney Disease)
Kidney is one of the main organs damaged by high blood pressure and at the same time, kidney is the important regulation organ of blood pressure. Nowadays, high blood pressure has been closely linked with Chronic Kidney Disease. Once symptoms such as swelling, nocturnal enuresis and foam in urine appear in patients, patients with high blood pressure should go to see doctor as soon as possible. Renal damage can be detected through urine routine test at the earlier time. Therefore, even patients with high blood pressure have no above mentioned symptoms, they should do urine test and renal function test regularly.
● High Blood Sugar
At present, in America and many European countries, Diabetic Nephropathy has been the major cause of renal failure. More than half of the patients who are undergoing dialysis are patients with Diabetic Nephropathy. For patients with Diabetes, they usually just care about the level of blood sugar and ignore their renal function. When swelling around their legs and hands appear, Diabetic Nephropathy always has developed into renal failure. Microalbuminuria is the early and important clinical indicator, so patients with Diabetes should take Microalbuminuria test regularly. Usually, one test per three to six months is the best.
● Hyperlipidemia
It is well known that patients with hyperlipidemia are likely to suffer from atherosclerosis and thus susceptible to coronary disease and cerebral apoplexy. However, apart from that, hyperlipidemia can also make renal artery have atherosclerosis, leading to the decrease of renal function. For patients with hyperlipidemia, they should pay much attention to their creatinine and take lipid-lowing medicines if necessary, so as to protect their kidneys.
● High Blood Uric Acid

When urate present saturated condition in blood, urate may deposit in kidney and then cause renal damage of uricemia, which show not only as urarthritis, tophus and freak joints, but also chronic interstitial nephritis, uric acid renal calculus and acute hyperuricemic nephropathy.

Why is Protein Limited for People with Chronic Kidney Disease (CKD)

It is well known that protein is the necessary nutrient substance for our human body. However, for patients with Chronic Kidney Disease (CKD), they are often asked to pay more attention to their diet, especially to the intake of protein. Then, is eating protein really unhealthy for patients with Chronic Kidney Disease?
Actually, protein is not a taboo for patients with Chronic Kidney Disease and patients are just asked to reduce the intake of it. We all know the mass of proteinuria is the major symptom of Chronic Kidney Disease, then how do the protein flow into patients’ urine?
For patients with Chronic Kidney Disease, protein can get into their urine in many ways. For example, proteinuria can not only results from the damaged glomerular filtration membrane, but also arises from the malabsorption of kidney tubules to protein. All in all, when our kidneys can not stop protein from being leaked, proteinuria(Proteinuria and Kidney Disease) will appear and meanwhile, we can say renal function decreases. For patients with damaged renal function, their remaining kidney function can not help to keep protein in their body. By this time, if they ingest too much protein, which has beyond the filtration ability of their kidneys, excessive protein will leak out from their body and the more protein patients with Chronic Kidney Disease ingest the more protein in their urine. Ingesting too much protein will burden our kidneys. With the great burden, patients’ remaining parts of kidneys will be damaged gradually. Therefore, patients with Chronic Kidney Disease should avoid ingesting too much protein.

For patients with proteinuria, the intake of protein should be based on their body weight. Usually, 0.6 gram to 1.0 gram of protein is suitable for each kilogram of body weight everyday. In addition, protein ingested by patients should be high-quality protein. This kind of protein is contained by fish, lean meat and egg white and so on.

What can Cause Aggravation of Chronic Nephritis

Chronic Nphritis is easy to relapse and repeated relapse can worsen illness condition. Therefore, in our daily life, we should avoid these inducements which can cause aggravation of Chronic Nephritis.
Ⅰ. Bacteria or virus infection. Infection such as infection of upper respiratory tract, asymptomatic bacteriuria, influenza, pharyngitis, and tracheobronchitis is the most familiar factor which can aggravate Chronic Nephritis.
Ⅱ. Overstrain. Overstrain, including strenuous exercise, work at night, physical labor and even sexual indulgence, is another cause of aggravation of Chronic Nephritis.
Ⅲ. Usage of medicines which can cause renal toxicity. Renal toxicity means toxic reaction of kidney caused by medicine. These medicines conclude gentamicin, kanamycin, strettomycin and aminoglycoside.
Ⅳ. Deteriorated Chronic Nephritis can arise from stress state. Stress state means the reaction of our body to the sudden stimulation such as bleeding of digestive tract, serious gastroenteritis, nausea, vomit(Nausea and Vomiting for Kidney Disease), diarrhea, hypotension, and anaphylactic shock. Any kinds of stress state can deteriorate Chronic Nephritis. As for our kidneys, when sudden stimulation appears, our kidneys have to increase the genaration of adrenal cortical hormone, so as to resist the stimulation.
Ⅴ. Some other factors can also cause acute exacerbation of Chronic Nephritis, such as disorder of water and electrolyte as well as dysequilibrium of acid-base.

Usually, under the action of these factors, symptoms such as proteinuria, swelling, aggravated hematuria, oliguria and even renal insufficiency appear in the same day or several days later. In addition, if these inducements can be removed and then people receive fundamental treatment timely, most of the patient will restore to previous state but for some people, their disease may turn into renal failure quickly. Therefore, in our daily life, patients with Chronic Nephritis should try to avoid these inducements.

Factors Causing the Development of Chronic Nephritis

Corresponding treatment is the best way of controlling our disease. However, sometimes, just receiving treatment can not help us solve the problem, it also need us to avoid the inducements, so as to guarantee the treatment effects. As for patients with Chronic Nephritis, preventing the appearance of the following factors can help to impede the progress of their disease.
● Cold and Infection.
Chronic Nephritis is immunologic disease and it often arises from cold an infectious disease. When our receive invasion from extraneous antigen such as bacterium and virus, our defensive Immunotherapy will be started, and consequently, antibody was generated. Combination of antibody and extraneous antigen forms the immune complex and this process is immunoreaction. Flowing with human blood and when these immune complexes deposit in glomeruli, glomerular permeability will be damaged, causing the leakage of masses of albumin and erythrocyte. Every time cold or infection occurs, glomerular will be damaged. Therefore, cold and nfection should be avoided for patients with Chronic Nephritis.
● Unreasonable Diet.
When patients suffer from Chronic Nephritis, their damaged kidneys can not bear heavy burden. Under the circumstance, ingesting too much protein or salt will aggravate their kidneys’ burden. Long-term renal burden will deteriorate their disease, so arranging a reasonable diet is significant for them to control their disease.
● Medicine Effects.
Most of the metabolin of medicines in our body are excreted by our kidneys. However, some medicines such as gentamicin, kanamycin, tetracycline and cephaloridnum can cause damage to our kidneys and even our healthy kidneys can be damage by these medicines, let alone patients with kidney problem. Hence, patients with Chronic Nephritis should avoid taking these medicines.
● High Blood Pressure(High Blood Pressure and Kidney Disease)
Chronic Nephritis can cause secondary high blood pressure; conversely, high blood pressure will aggravate Chronic Nephritis. Long-term spam and induration of capillaries may cause renal ischemia and glomerulosclerosis which are the major reasons of renal atrophy and renal failure. Seeing from this point, controlling blood pressure is necessary for patients with Chronic Nephritis.
● Hyperlipidemia
Hyperlipidemia can aggravate the damage of glmerular capillaries, and affect the recovery of kidneys, so prevent the occurrence of Hyperlipidemia is also very necessary.
● Influences of Spirit

A good mental state can promote the recovery of patients. On the contrary, poor mental state will deteriorate our disease. If patients with Chronic Nephritis live in an anxious, dread, worried and nervous state for a long time, their immunity will decrease. As a result, their disease will be worsened.

What Can Cause Back Pain for People with Polycystic Kidney Disease

No matter at home or overseas, Polycystic Kidney Disease is a common disease. For patients with Polycystic Kidney Disease, they have many symptoms such as high blood pressure, hematuria and back pain. Among these symptoms, back pain is the dominant one, then what can cause back pain for patients with Polycystic Kidney Disease?
Polycystic Kidney Disease is genetic disease and it means there are many cysts in both renal cortex and renal medulla. Usually, as people grow, cysts also enlarge and when cysts develop to a certain level, back pain emerges. For patients with Polycystic Kidney Disease, back pain can be caused through different pathological changes.
Firstly, enlarged kidneys or cysts, massive haemorrhage inside cysts, or stretching to renal capsule and tractive renal vascular nerve all can cause pain in the location of kidneys.
Secondly, associated with lithiasis or bleeding in their cysts, patients with Polycystic Kidney Disease are easy to feel back pain, because some small stones and blood clot may block their ureter. Blocking of ureter is one of the major causes of back pain.
Thirdly, physical activities, long time walking or sitting also are the factors for back pain.
Fourthly, patients with Polycystic Kidney Disease are easy to have lithangiuria such as renal stone and ureteral calculus. Owing to urinary scour or moving, stone also move, causing pain in the location of their kidneys.
Fifthly, when patients with Polycystic Kidney Disease get urinary tract infection, they usually feel pain in their lower back.
Sixth, renal fracture caused by rapid increase can give rise to perinephric hematoma or abscess, which is another cause of back pain for patients with Polycystic Kidney Disease.

For Polycystic Kidney Disease, the optimal therapeutic method is control and shrink cysts. Although the gene of this disease is unchangeable, damaged cyst parietal cell can be restored. Therefore, for patients with Polycystic Kidney Disease, choose the effective treatment is vital.

Why Does Salt Help to Increase High Blood Pressure

We all know that salt is limited for patients with high blood pressure, then why does salt help to increase high blood pressure(High Blood Pressure and Kidney Disease)?
★ Salt is abundant in sodium. If we ingest too much salt, then excessive sodium will be detained in our body. Retention of sodium will inevitably cause retention of water. Retention of great water and sodium will give rise to the increase of fluid outside the cells, leading to the increase of blood pressure.(High Blood Pressure and Kidney Disease)
★ Due to the concentration gradient, increased sodium outside cells will cause the increase of sodium inside the cells. As a result, intracellular edema appears. Edema of smooth muscle cell in small artery will lead to the narrowing of lumen. Consequently, blood pressure increases.
★ Increase of sodium in cells can restrain the exchange of sodium and potassium, leading to the increase of calcium. These calcium mainly get into cells through susceptibility calcium channel. Increased calcium in the cells of vascular smooth muscle cells will cause the shrink of smooth muscle, leading to the increase of blood pressure.
★ Intake of too much sodium increases the receptor of type Ⅱ angiotensin. Type Ⅱ angiotensin has strong ability of shrinking of blood vessels. Increase of receptor of type Ⅱ angiotensin means the increase of type Ⅱ angiotensin. As a result, high blood pressure appears.
★ Great amount of sodium can suscitate sympathetic nerve centre, causing the increase of hypothalamus norepinephrine and then strengthen the stimulation to hypothalamus neuron, which will increase the blood pressure.
★ Increase of sodium in presynaptic membrane cells of sympathetic nerve ending will promote the release of norepinephrine. Norepinephrine often causes the shrinking of blood vessels, and as a result, blood pressure increase.

Increasing blood pressure through ingesting too much salt is just one of the methods. For patients with Chronic Kidney Disease, ingesting too much salt can not only cause the increase of blood pressure, but also cause the aggravation of swelling. Therefore, in their daily life, they should avoid ingesting too much salt.