2014年12月30日星期二

Pathological Process of Hypertensive Nephropathy

Hypertensive Nephropathy is a very common kidney disease, which is caused by Hypertension. Hypertension is one of principle causes of nephropathy. But not all patients with Hypertension will suffer from Hypertensive Nephropathy.
If internal pressure of renal blood vessels is normal with the regulating of glomerular arteriole, as well as glomerular filtration rate (GFR), Hypertension will not cause Hypertensive Nephropathy. Only long-term Hypertension commonly more than 10-15 years often induces kidney disease. Then what is the whole pathological process of Hypertension Nephropathy?
Long-term Hypertension brings "three highs" to glomeruli, that is, glomerular blood pressure, glomerular high perfusion, glomerular high filtration. The 'three highs" make blood stream flow fast in glomerular blood vessels. Persistant fast blood stream stimulates glomerular blood capillary and activates glomerular endothelial cells. The active glomerular endothelial cells consume amounts of oxygen, making glomeruli ischemia and anoxia. And then glomerular endothelial cells are damaged and appeal many inflammatory factors in blood. These inflammatory cells activate renal fibrosis.
Besides the above aspect, the inflammatory factors in glomeruli release into renal interstitium and stir up inflammatory reaction. As last, fibrosis of renal tubular epithelial cells and renal interstitium occurs.
All in all, phenotype transformation of renal intrinsic cells occurs under influence of long-term Hypertension. The damaged intrinsic cells not only appeal inflammatory factors but also secrete more extracellular matrix. These two kinds of substances both can stimulate renal fibrosis and glomerulosclerosis. Eventually, renal functions break down completely.
Therefore, aiming at the pathology of Hypertensive Nephropathy, first what patients do is to control blood pressure keeping a normal level. This can relieve the stimulation to renal blood vessels. Second, patients should receive proper and timely treatment of kidney disease to avoid worsening disease. it is quite important for patients to know that western medicines are just affect on superficial symptoms but have no any treatment effects on diseases. Only receiving western treatment can delay the pathological treatment of kidney disease , in addition to many side effects. So patients should focus on Chinese medicine treatment which is real treatment of kidney disease without any negative effects. Shijiazhuang Kidney Disease Hospital has applied Micro-Chinese Medicine Osmotherapy as the core treatment method to treat kidney disease, with Immunotherapyation and comprehensive blood purification technology as assistant treatment. This syImmunotherapyic treatment technology has proven tremendously effective in clinical practices.
First, we adopt Micro-Chinese Medicine Osmotherapy to dilating blood vessel with functions of anti-inflammation, anticoagulation, and degrading extracellular matrix. This step is to better micro renal circulation and prepare for repairing damaged cells and recovering normal renal functions.
Second, we use blood purification to clear most of toxic substances and wastes to supply a better treatment environment.
Third, Immunotherapy transplantation technology is to repair the damaged cells and rebuild the renal normal structure, recovering the renal functions.
In the whole process, we need the western medicines as the assistant treatment to control the severe clinical symptoms but as little as possible.

These four great technologies perform tremendous curative effect in treating kidney disease as a whole Immunotherapy, which occupies more and more important position in the field of kidney disease treatment. This characteristic treatment Immunotherapy has brought wellness to innumerable patients with kidney disease! If you want to know more detailed information, you can consult our online experts or send e-mail to me.

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