2014年12月20日星期六

Causes of Kidney Stone

Kidney Stone is a common complication of Chronic Kidney Disease (CKD) and it refers to the calculus formed at renal calyx, renal pelvis, and the conjunction of renal pelvis and ureters. Compared with the calculus at other parts of body, kidney stone will directly cause damage to kidney, thus early treatment is extremely necessary. However, what are the causes of kidney stone on earth?
It is known to all that kidney is the main excretory organ of the body which is in charge of the excretion of urine. However, when the solute contained in urine forms deposition due to various causes, the deposition will be retained in the kidney. As the deposition accumulates gradually, finally it will form Kidney Stone.
Then, what should account for the deposition of the solute in urine? Specifically, it is related with the diet. The intake of some ingredients in daily life contributes to the formation of calculus:
Oxalic acid: Consumption of much oxalic acid is one of the main factors to cause Kidney Stone. Lots of daily fruits and vegetables contain an abundant of oxalic acid, for example, spinage, beans, tomatoes, potatoes, bamboo shoots, plum, grapes, oranges, etc.
Purine: Disorders of purine metabolism is the another factor to cause Kidney Stone. Purine in the body will metabolize uric acid, which will accelerate the deposition of oxalate in the urine. If one takes much food containing purine, like animal innards, seafood, peanuts,etc, meanwhile there’s a metabolic error of purine, causing constant accumulation of oxalate, finally it will forms kidney stones.
Lipid: Much intake of lipid will promote the intestinal absorption of calcium oxalate, and then the calcium oxalate will run through kidney by urine. If simultaneously, the patient has renal excretion disorders which caused by Chronic Kidney Disease (CKD) or other kidney diseases, causing calcium oxalate accumulating, kidney stone will appear easily.
Protein: Protein contains many substances which contribute to the formation of calcium oxalate. Besides, it can also help the absorption of calcium. A large consumption of protein will increase the content of oxalate, calcium and uric acid in urine. If the excess substance can not be excreted in time, the patients are quite likely to have kidney stones. This factor exactly explains the reason why kidney stones are commonly seen among the patients in the developed areas.

Therefore, in order to prevent the occurrence of kidney stones and the development of Chronic Kidney Disease, people, especially patients with Chronic Kidney Disease who can not excreted urine as the normal, should attach enough importance to their diet by conforming to the rule: drink more water, balance the nutrition intake, and take more exercises. I wish this article can be helpful.

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