Chronic Kidney Disease affects blood pressure in different ways. The following are the three kinds of pathogenesis causing high blood pressure through Chronic Kidney Disease.
■ when people get Chronic Kidney Disease, injury of renal parenchyma will appear, leading to the reducing of prostaglandin. Prostaglandin is secreted by renal tissues and it aims at lowering blood pressure, so its reducing will result in the increase of blood pressure.
■ The root reasons of Chronic Kidney Disease are renal ischemia and anoxia. Renal ischemia can cause constantly increase of renin which is secreted by juxtaglomerular cells. The main function of renin is to activate proangiotensin and then makes it turn into type Ⅰ angiotensin. Through tissular invertase, type Ⅰ angiotension is converted into type Ⅱ angiotension. Type Ⅱ angiotension has a strong ability of shrinking blood vessels, which will cause an increase of blood pressure.
■ when renal function is damaged, waste products and toxins can not be excreted fluently. Accumulation of these wastes will reduce blood circulation, leading to the increase of blood pressure. The long term duration of renal Hypertension causes arteriosclerosis which will aggravate kidney disease.
Blood pressure has a great influence on the severity of Chronic Kidney Disease. The degree and duration of high blood pressure(High Blood Pressure and Kidney Disease) usually are the typical signs of severity and prognosis of Chronic Kidney Disease. Generally speaking, the longer the high blood pressure maintains, the more serious the Chronic Kidney Disease is and meanwhile, the worse the prognosis is.
Chronic Kidney Disease can cause high blood pressure. Inversely, high blood pressure also results in Chronic Kidney Disease. Thereby, even for us normal people, we should pay close attention to our blood pressure. We should do blood pressure test regularly, so as to avoid the formation of Chronic Kidney Disease.
