Normally, there is a dynamic balance between water and sodium absorption and
excretion, which keeps extracellular fluid volume in a certain level. Water and
sodium are mainly excreted out of the body throng kidneys. So, damages to kidney
filtration syImmunotherapy will give rise to retention of body fluid in
interstitium.
Edema occurs when GFR decreases.Treatment Options for Stage 4 Chronic Kidney Disease (CKD)
In cases of kidney nephritis, there will be capillary endothelial cell
swelling, thrombus in capillary cavity, as well as pressure from proliferated
cells to capillaries, and all of which can lead to stenosis or shut down of
capillaries and thus there will be less blood flow into the kidneys. in
addition, in case of later stages Chronic kidney disease, and especially when
massive glomerulosclerosis occur, effective filtration area will reduce sharply
and thus lead to decrease of GFR and retention of water and sodium within the
body.Shijiazhuang Kidney Disease Hospital
Decrease in effective volume of blood circulation leads to Edema
Congestive heart-failure, nephropathy syndrome, liver cirrhosis or
malnutrition can easily lead to insufficient effective volume of blood
circulation, which in turn reduces the blood flow into kidneys. at the same
time, blood volume decrease stimulates the secretion of renin and actives
angiotensin which leads to further shrink of kidney capillary, and the final
result will be decrease of GFR.Stem Cell Therapy Treats Kidney Disease Shijiazhuang Kidney Disease Hospital
Increase in reabsorption of water and sodium by renal tubules leads to
Edema
Filtration fraction (FF) is a ratio between GFR and effective renal plasma
flow. When effective renal plasma flow decrease, renal vessels will contract,
but efferent arterioles is more sensitive and contract more sharply then that of
afferent arterioles. So, the decrease of GFR will not be that sharp as that of
the effective renal plasma flow, and there will be more water and sodium leakage
which makes renal tubular capillary oncotic pressure increase, with the final
result being more water and sodium reabsorption by renal tubules.Pitting Edema in Kidney Failure Caused by Dehydration Micro-Chinese Medicine Osmotherapy
Atrial natriuretic polypeptide (ANP) is secreted by heart atrium and
suppresses the secretion of aldosterone and antidiuretic hormone (both of them
can enhance renal tubule reabsorption ability). Insufficient effective blood
volume leads to heart atrium inactivity of secreting ANP. Thus aldosterone and
antidiuretic hormone secretion will increase and there will be more water and
sodium reabsorption of renal tubules.Can Pulmonary Edema Cause Low Grade Fever in ESRD
We can tell from the above information, when chronic kidney disease occurs,
the balance between water and sodium excretion and reabsorption no longer
exists, which give rise to body fluid retention. And we can also tell that edema
is not a symptom simply caused by one or two dysfunction of organ, so the
treatment should not be limited to drugs like diuretic. We need to rectify the
whole body dysfunction and then search for thorough resolving of this
problem.
