Symptoms or Signs of Chronic Kidney Disease

Kidney disease is a kind of disease that derived from kidney primarily or secondary to other organs with major clinical manifestations in urine abnormalities and some symptoms reflected in parts of the kidneys. In traditional Chinese medicine, their clinical manifestations also include some symptoms in endocrine and reproductive syImmunotherapy due to a wider scope of definition on kidney. A brief introduction of nephrotic clinical manifestations and their meanings will be presented in the following:
A. Abnormalities of Urine Volume
1. Oliguria or anuria: oliguria refers to a urine output that is less than 400 mL or 17 mL/hour; anuria means nonpassage of urine, in practice is defined as passage of urine less than 50 milliliters of urine in a day. Both of them are usually associated with kidney failure.Treatment Options for Stage 4 Chronic Kidney Disease (CKD)
2. Polyuria: it refers to passage of urine more than 3000ml or 2ml/ minute. Causes of polyuria include too much water intake, lesions in renal tubules and renal intertitum, increased output of water in the kidneys, too much production of substances like glucose, etc.Acupuncture for Kidney Disease
3. Nocturia: it refers to that urine output (18 pm to next 6am) is more than half of daily urine output, usually associated with renal insufficiency. Besides, cardiac insufficiency and some psychicfactors may also cause nocturia. However, frequent urination without any increase of urine output does not mean nocturia.
B. Abnormal urination.Is Stage 4 CKD (Chronic Kidney Disease) Curable
1. Urinary frequency, urinary urgency, and odynuria: urinary frequency refers to frequent urination (normal people 4-6 times/ day, 0-2 times/night on average). Urinary urgency refers to urgent urination once a person feels like urinating or just after one time of urination. It often loses its self-control. Odynuria refers to the pain or burning pain when passing urine. The coexistence of the above symptoms is one of the characteristic menifastations of urinary inflammation
2. uroschesis: it refers that urine can not be passed out but stay in gall bladder due to urination disturbance, usually associated with partial or complete obstruction of urethra, medications, nervous diseases, etc.
3. Uracratia: it refers to any involuntary leakage of urine, commonly seen in abnormalities in anonamy of urinary tracts, malfunction, neuropathic bladder, etc.Stem Cell Therapy Treats Kidney Disease.What Is the Solution to Stop Dialysis Treatment
C. Lumbago
1. Renal colic: the pain breaks out suddenly and often radiates to lower abdomen, vulvae, inner thighs, etc. The pain is often intermittently colicky due to blockages like calculus, blood clots, necrotic tissues in ureter, etc.
2. Dull pain and bursting pain in the kidneys: renal pains caused by urinary include: 1). Pains caused by the case that swelling kidney props against renal capsule, commonly seen in acute nephritis, acute nephropyelitis, hydronephrosis, polycystic kidney, kidney caner, nephroptosis, etc. 2) lumbago caused by disease around the kidneys, such as abscess around the kidneys, inflammations around the kidneys caused by renal infarction, breaks of renal cysts, hematoma around the kidneys, etc. However, in many case, lumbagos also arise from spinal diseases or parenchyma diseases around the spine. What is more, pains from pancreas, gallbladder, stomach, etc, often radiate to the lower back too.Stem Cell Therapy for CKD Stage 5 Patients
D. Edema.Facial Edema in Nephrotic Syndrome
Kidney is the major organ to discharge water. When the illness attacks the kidney, water can not be removed but kept in the body and causes edema. It may be mild or severe. Mild edema may not be seen from appearance but has a gaining in weight (invisible edema), or a slight swelling in the eyelids in the face. Severe cases involve obvious anasarca, sometimes even pleural effusion, ascites, and 10kg increase in weight (severe edema). The causes are included as follows:
1. When there is an illness in the kidneys, the renal filtration will have a decrease in filter area, permeability and bloodstream volume. But renal reasorption works well. In this condition, oliguria will come up.
2. The permeability of capillary wall all over the body will increase due to immune damages of renal disease, which cause seepage of water from plasma to interstitial space.
3. The renal blood flow diminution and blood insufficiency in the renal parenchyma due to kidney disease will increase rennin secretion. This kind of angiotensin will stimulate adrenal cortex to secrete more aldosterone, resulting that more water and natrium will be reabsorbed back to the bloodstream.

4. Long-term of proteinuria will result in protein insufficiency in the body and progress to hypoproteinaemia. In that case, the plasma colloid osmotic pressure will be reduced, which retain the extracellular fluid in the interstitial space, causing edema. In addition, hypoproteinemiacan may engender a decrease of effective blood volume, and then increased secretions of aldosterone and antidiuretic hormone. Therefore, the kidneys reabsorb more water and sodiumin, causing edema.