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2015年6月5日星期五

A Typical Manifestation of Chronic Kidney Disease

Chronic Kidney Disease can be manifested through many different manifestations, and large quantity of proteinuria is one of the dominant manifestations. Proteinuria is invisible, so it is difficult for us to judge whether it exists. The formation of proteinuria has a close relation with glomerular filtration rate (GFR). When GFR is lower than normal value (≥90 mL/min/1.73 m2), we can say that our renal function decreases.
Proteinuria of Chronic Kidney Disease can be divided into three types which include glomerular proteinuria, tubular proteinuria and renal tissular proteinuria.
● According to the injury level of filtration membrane and composition of proteinuria, glomerular proteinuria can be divided into two types: Selective proteinuria and Non-selective proteinurina.Proteinuria and Kidney Disease
Selective proteinuria takes albumin as its major ingredient, accompanied by small amounts of low molecular weight protein. There is no large molecular weight protein such as IgA, IgG, IgM, C3 and C4. The typical disease of this kind of protein is Nephritic Syndrome.Treatment for Kidney Disease Patients With Weight Gain and Proteinuria and Is It Safe for Stage 4 CKD Patients to Dye Hair
The appearance of Non-selective protein indicates glomerualr capillary wall is damaged greatly. Non-selective proteinuria usually appears among patients with glomerular disease. There exists large molecular weight protein, albumin with proper molecular weight, and protein with low molecular weight in urine. The appearance of Non-selective proteinurina often suggests a poor prognosis.
● Tubular proteinuria is often seen among patients with interstitial nephritis, renal arterial embolism and renal vein thrombosis caused by different reasons.
● Renal tissular proteinurina is also called secretory proteinuria. It results from the blend of urine and protein produced by kidney tubules during the formation of urine. The protein can be caused not only by metabolism and inflammation of renal tissues, but also by stimulation of medicines to urethral tissues.How Many Grams of Protein Per Day Is a Safe Level in Stage 3 CKD
Chronic Kidney Disease has various manifestations and large amount of proteinuria is the typical one. Now after the brief introduction about proteinuria you must have a general understand about it. Appearance of large quantity of proteinuria means patients’ kidney is damaged. Thereby, the detection of it is very important if you suspect you get Chronic Kidney Disease.

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