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One Cause of Edema in Chronic Kidney Disease

Edema is an abnormal accumulation of fluid beneath the skin or in one or more cavities of the body. It is one of the common symptoms of Chronic Kidney Disease; so many patients concern with its causes.
Before we talk about the causes of edema, let’s know about the renal functions firstly. First of all, by regulating urine volume, our kidneys can help us to maintain the levels of water in our body. When blood flow into glomerular, water and other crystalline materials melted in the blood will be filtered out and then get into the kidney tubules under the normal filtration pressure. The epithelial cells of kidney tubules will excrete urine and the urine volume will depend on the water volume inside our body. Apart from that, our kidneys also have the function of keeping our body in a normal acid-base balance. Our kidney can excrete the acid-containing substances which are produced by our body during metabolism. Meanwhile, our kidneys reabsorb bicarbonate, so as to regulate the volume of acid substances and alkali substances.Swelling and Kidney Disease and Facial Edema in Nephrotic Syndrome and Can Pulmonary Edema Cause Low Grade Fever in ESRD and Pitting Edema in Kidney Failure Caused by Dehydration
In the process of forming urine, glomeruli play the function of filtration, so when glomeruli are damaged, filtration area will reduce. Obviously, the fluid volume that can get through glomeruli will also reduce, so as to decrease the glomerular filtration rate. When the excessive water and acid-containing substances can not be filtered out fluently, they will accumulate in our body, so as to decrease our urine volume. That is the reason why patients with symptom of swelling usually have oliguria or even anuria. In addition, with the accumulation of these water and acid-containing substances in our body, swelling will appear.

Edema brings a lot of inconvenience for people with Chronic Kidney Disease, for example, it makes them look fat and ugly. What’s more, edema can cause great damage to their body, for example, the long time retention of water and waste products among tissues will increase the distance between histocyte and tiny blood capillary, so that the nutrient substances in the blood can not reach each cell fluently. Due to the damages caused by edema, patients with Chronic Kidney Disease should receive treatment as soon as possible.

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