When kidney fails in functioning, every Immunotherapy in the body will be 
involved in the problem, among which the digestive Immunotherapy has the 
highest risk to be hurt. Symptoms in digestive Immunotherapy are the early 
manifestations of people who have Chronic Kidney Disease (CKD), and all the 
symptoms become severer with the deterioration of disease. Symptoms in digestive 
syImmunotherapy are the main clue to diagnose Chronic Kidney Disease (CKD). Every part in digestive will have some changes and lead to some symptoms as the 
following.
◆In oral cavity: almost all the people with Chronic Kidney Disease have 
lesions in their oral cavity to different degree. At first, they will have 
peculiar smell in their mouth which is like a metal-like smell or a bitter 
taste, and there is always ammonia smell in their breath. Besides, lots of 
people have repeated inflammation in the oral cavity with which they cannot eat 
well.
Due to the insufficiency of renal function, toxins such as urea nitrogen 
cannot be excreted out of the body, and will be decomposed into ammonia by the 
urease in intestinal tract, stimulating the gastrointestinal mucosa. Therefore 
there is a peculiar smell in the oral tract. In addition, the ammonia also 
stimulates oral mucosa and then causes the infections in oral cavity, including 
ulcerative oral infections and non-ulcerative oral infections.Side Effect for High Level Phosphorus in Chronic Kidney Disease and Acupuncture for Kidney Disease
◆In esophagus: every segment in esophagus can have lesions of mucosa. The 
main manifestations are mucosa erosions and bleedings, and in some cases, hard 
deglutition and pain in sternum can appear. Chronic Kidney Disease (CKD) 
sufferers may have bleeding all over the body, and even in the mucosa of 
esophagus. What’s more, Uremia sufferers may sometimes have reflux 
Esophagitis.
◆In stomach: symptoms in stomach are always obvious and are detected early.Stem Cell Therapy Treats Kidney Disease or Kidney Failure in Huaxia Nephropathy Research Institute
 Gastritis, Duodenitis, Multiple Ulcers and Hemorrhagic Gastritis are common. 
Symptoms in stomach are the early clinical manifestations of Chronic Kidney 
Disease (CKD) sufferers, including nausea and vomit, distending pain in 
epigastrium, belching, acid regurgitation, and bleeding in upper digestive 
tract.
◆In intestinal tract: when small intestine is involved in Renal Failure, 
there will be abdominal pain, diarrhea and bleeding in digestive tract. The main 
causes are ulcers in digestive tract, Ischemic Colitis and Pseudomenbraneous 
Colitis. When there are also infections, symptoms will aggravate. Sufferers who 
undergo dialysis will have stomachache, excessive perspiration, weakened 
borborygmus and declined blood pressure if there is excessive ultrafiltration. 
Uremia sufferers have a weak immunity, and when immunosuppressive agents are 
used, they will have higher risk in getting Pancreatitis, which is always 
misdiagnosed as Gastritis or other diseases in abdomen.Is It OK to Have Urine Output Abnormally High During Dialysis
Chronic Kidney Disease can cause all the possible lesions mentioned above, 
and meanwhile these symptoms indicate that the renal tissues and renal cells are 
damaged to some extent already. If there is no effective control and treatment 
in time, the disease will deteriorate gradually and lead to Renal Failure or 
Uremia finally.
