In the first stage, patients with Diabetic Nephropathy can not feel any discomfort. Through renal function test, glomerular filtration rate can be found to have increased, which result from the hypertransfusion station of glomeruli.
In the second stage of Diabetic Nephropathy, there are no distinct symptoms. The urine protein excretion of patients is normal at rest with a rate lower than twenty microgramme per minute. However, after patients do some exercises, there will be more proteinin their urine. In this stage, patients’ glomerular filtration rate can keep in a high level or decrease to normal state. If patients do renal biopsy during this stage, the early pathological change can be found.
The third stage is also called early stage of Diabetic Nephropathy.
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In this stage, some manifestations appear such as high blood pressure and persistent microalbuminuria. Persistent microalbuminuria with proteinuria excretion rate of 20 to 200microgramme per minute is the mark of this period. However, the result of urine protein detection in urine routine test still shows negative. During this stage, glomerular filtration rate is roughly normal and high blood pressure appears. This stage is significant, because once Diabetic Nephropathy develops to next stage, this kind of Chronic Kidney Disease will become irreversible.How to Treat Eye Problems for Diabetic Nephropathy
The forth stage is clinical Diabetic Nephropathy. The major characteristic of this stage is macroalbuminuria with the volume more than 3.5 gram per day and the result of urine protein detection in urine routine test shows positive. During urination, patients with Diabetic Nephropathy can find a lot of foams in their urine and these foams do not fade away within a long time. Moreover, symptoms such as high blood pressure and swelling appear in patients.Is It Safe for Diabetic to Use Sodium Polystyrene Sulfonate to Lower Potassium
The last stage is renal failure and it is called end stage of renal disease in clinic. With the appearance of massive proteinuria, this disease continuously deteriorates until to renal failure. During this period, the volume of urine protein of patients does not decrease. In this stage, high blood pressure and swelling are more severe. Besides, anemia and backache appear. Meanwhile, because patients with Diabetic Nephropathy in end stage are usually malnourished, they are more prone to getting some complications such as retinopathy.
