As a patient with Chronic Kidney Disease, you must know swelling and less
urine are the two symptoms of Chronic Kidney Disease. Less urine belongs to the
abnormal urination and swelling refers to the retention of excessive water and
sodium in our body. Although these two are just symptoms of Chronic Kidney
Disease, is there any relationship between them? Kidney Disease Symptoms and Treatment
Before we talk about the relationship between them, let’s find out the roots
causes of these two symptoms. First of all, we all know our kidneys have a lot
of functions such as maintaining the balance of acid-base, excreting waste
products and promoting the generation of urine. Moreover, according to the water
volume in our body, our kidneys can help us regulate the urine volume and this
is the reason why we usually have frequent urination when we drink a lot of
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As to the swelling, it arises from the retention of excessive water and
sodium. Generally speaking, with the blood fluid, sodium and water in blood are
filtrated by glomeruli and then get into renal tubules which have reabsorption
function and will absorb most of these fluids. Hence, if renal tubules are
damaged and reabsorb almost all the fluids, then the excessive water and sodium
reabsorbing by renal tubules in blood will pile up in the body, leading to the
occurrence of swelling. Besides this, another condition will cause less urine as
well and it is the damage of glomerular filtration membrane. Just as we have
mentioned just now, glomeruli can help us filtrate blood, so if filtration
membrane is damaged and can not filtrate blood any more, then water and sodium
will accumulates in our body as well.