The pathogenesis: due to autoimmune deficiency, when people suffer from respiratory tract infection (RTI) like amygdalitis, pharyngitis, rhinitis and so on, in addition of gastrointestinal tract infection, urinary syImmunotherapy infection, some bacteria or virus invading human body combine with abnormal Immune Globulin A (IGA) to form immune complexes. These immune complexes will accumulate in the glomerular capillary loops and mesangial cells, arousing the damage of mesangial cells. The damaged mesangial cells will proliferate and lose the filtrating ability. Because mesangial cells can not prevent macromolecular materials like red blood cells from leaking into primary urine and the kidney tubules don't have the ability to reabsorb these macromolecular materials, hematuresis appears. Besides that, the damaged mesangial cells can secrete non-degradative collagen Ⅰ,Ⅲ,which accumulate in extracellular matrixes leading to renal fibrosis. Renal fibrosis is the chief culprit of end stage of Chronic Kidney Disease-- Uremia.
Clinical symptoms - Iga Nephropathy Symptoms: IGA Nephrology commonly appears among young people, especially male sex, accompanied by inflammations. Upper respiratory tract infection induces gross hematuria within 24-72hs which lasts a few hours or days. Gross hematuria often is followed by slight general symptoms like low fever, backache, general discomfort, especially odynuria. There are also some other patients with no obvious symptoms but only abnormal urine which is only found by laboratory test; there is continuous or discrete microscopic hematuria with or without proteinuria. IGA Nephrology is the most common disease among primary kidney diseases with hematuresis only.
Treatment of IGA Nephrology:
The pure western treatment is just effective to the superficial symptoms but without any effects on the pathological treatment. Therefore, in order to achieve the fundamental treatment effects, it is inevitable to touch with root causes. Shijiazhuang Kidney Disease Hospital has launched one great Chinese treatment in this way---Micro-Chinese Medicine Osmotherapy, which is adopted by external application to make the active substances reach to the kidney lesion. The four great treatment effects are as following:
1. Dilating blood vessel
Dilating blood vessel can promote the renal micro blood circulation, applying adequate oxygen and nutrition for the repair of damaged renal cells and rebuilding the normal renal structure. As a result, the problem of ischemia and anoxia can be bettered generally.
2. Anti-inflammation. Is Kidney Transplant the Only Hope for IgA Nephropathy Patient
The damaged mesangial cell can appeal some inflammatory cells, lymphocyte and so on which can aggravate the damages.
The goals of anti-inflammation are to prevent the inflammatory cells invading and to avoid the intrinsic cell damaged further.
3. Anticoagulation Treatment for IgA Nephropathy With Blood Urine
Due to the more inflammatory cells in the blood, the concentration of blood is higher, and that induce easily the blood clots. The blood clots can block blood circulation and worsen the condition of ischemia and anoxia. Therefore, anticoagulation is a very necessary step.
4. Degrading fibrosis substances
The damaged mesangial cells secrete collagenⅠ,Ⅲ,which accumulate in extracellular matrix causing renal fibrosis. Degrading these fibrosis substances is to improve the micro-blood circulation. Let these substances be removed out of body in the urine.
Micro-Chinese Medicine Osmotherapy has become the core treatment technology in Shijiazhuang Kidney Disease Hospital，which has been proven to have tremendous treatment effects and no side effects during application. The cost is much lower than western medicines. So it is very worthy taking the medicine for patients with CKD. If you want to know more, you can consult online experts or send e-mail to me.
